Body temperature rises following improvement of depression with ECT.
Ann Clin Psychiatry
; 30(3): 196-199, 2018 08.
Article
em En
| MEDLINE
| ID: mdl-30028893
ABSTRACT
BACKGROUND:
Recent studies have reported hyperthermia is an efficacious treatment for depression. Thus, we hypothesized that a proven depression therapy such as electroconvulsive therapy (ECT) would be associated with an increase in body temperature.METHODS:
A retrospective chart analysis was conducted on 33 participants who recovered from depression after a course of ECT. All were hospitalized for recurrent, severe symptoms and had no previous ECT treatment. Oral temperature recordings before and after the first and last ECT treatments were collected for each participant. Statistical analysis was performed using paired t test.RESULTS:
No significant change in mean oral temperature occurred after the first ECT, but a significant increase from baseline was observed after the final ECT treatment when depression symptoms had clinically remitted (P < .009).CONCLUSIONS:
Improvement in clinical depression with ECT is correlated with an increase in body temperature. Body temperature may have potential as a biomarker for ECT efficacy, and possibly for antidepressant pharmacotherapies.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Temperatura Corporal
/
Transtorno Depressivo Maior
/
Eletroconvulsoterapia
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Ann Clin Psychiatry
Assunto da revista:
PSIQUIATRIA
Ano de publicação:
2018
Tipo de documento:
Article