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A novel dual PPAR-γ agonist/sEH inhibitor treats diabetic complications in a rat model of type 2 diabetes.
Hye Khan, Md Abdul; Kolb, Lauren; Skibba, Melissa; Hartmann, Markus; Blöcher, René; Proschak, Ewgenij; Imig, John D.
Afiliação
  • Hye Khan MA; Department of Pharmacology & Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA. abhkhan@mcw.edu.
  • Kolb L; Department of Pharmacology & Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.
  • Skibba M; Department of Pharmacology & Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA.
  • Hartmann M; Institute of Pharmaceutical Chemistry, Goethe-University of Frankfurt, Frankfurt am Main, Germany.
  • Blöcher R; Institute of Pharmaceutical Chemistry, Goethe-University of Frankfurt, Frankfurt am Main, Germany.
  • Proschak E; Institute of Pharmaceutical Chemistry, Goethe-University of Frankfurt, Frankfurt am Main, Germany.
  • Imig JD; Department of Pharmacology & Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA. jdimig@mcw.edu.
Diabetologia ; 61(10): 2235-2246, 2018 10.
Article em En | MEDLINE | ID: mdl-30032428
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: PPAR gama / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 2 / Inibidores Enzimáticos / Epóxido Hidrolases Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Diabetologia Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: PPAR gama / Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 2 / Inibidores Enzimáticos / Epóxido Hidrolases Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Diabetologia Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos