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A Semi-Mechanistic Population Pharmacokinetic Model of Nusinersen: An Antisense Oligonucleotide for the Treatment of Spinal Muscular Atrophy.
Biliouris, Konstantinos; Gaitonde, Puneet; Yin, Wei; Norris, Daniel A; Wang, Yanfeng; Henry, Scott; Fey, Robert; Nestorov, Ivan; Schmidt, Stephan; Rogge, Mark; Lesko, Lawrence J; Trame, Mirjam N.
Afiliação
  • Biliouris K; Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, Florida, USA.
  • Gaitonde P; Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, Florida, USA.
  • Yin W; Biogen Idec, Cambridge, Massachusetts, USA.
  • Norris DA; Ionis Pharmaceuticals Inc., Carlsbad, California, USA.
  • Wang Y; Ionis Pharmaceuticals Inc., Carlsbad, California, USA.
  • Henry S; Ionis Pharmaceuticals Inc., Carlsbad, California, USA.
  • Fey R; Ionis Pharmaceuticals Inc., Carlsbad, California, USA.
  • Nestorov I; Biogen Idec, Cambridge, Massachusetts, USA.
  • Schmidt S; Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, Florida, USA.
  • Rogge M; Biogen Idec, Cambridge, Massachusetts, USA.
  • Lesko LJ; Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, Florida, USA.
  • Trame MN; Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, Florida, USA.
CPT Pharmacometrics Syst Pharmacol ; 7(9): 581-592, 2018 09.
Article em En | MEDLINE | ID: mdl-30043511
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligonucleotídeos / Atrofia Muscular Espinal / Modelos Biológicos Limite: Animals Idioma: En Revista: CPT Pharmacometrics Syst Pharmacol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligonucleotídeos / Atrofia Muscular Espinal / Modelos Biológicos Limite: Animals Idioma: En Revista: CPT Pharmacometrics Syst Pharmacol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos