Determination of Novel Highly Effective Necrostatin Nec-1s in Rat Plasma by High Performance Liquid Chromatography Hyphenated with Quadrupole-Time-of-Flight Mass Spectrometry.

Mikus, Peter; Pecher, Daniel; Rauová, Drahomíra; Horváth, Csaba; Szobi, Adrián; Adameová, Adriana

Mikus, Peter; Pecher, Daniel; Rauová, Drahomíra; Horváth, Csaba; Szobi, Adrián; Adameová, Adriana.

Afiliação

Mikus P; Department of Pharmaceutical Analysis and Nuclear Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Odbojárov 10, 832 32 Bratislava, Slovak Republic. mikus@fpharm.uniba.sk.
Pecher D; Toxicological and Antidoping Center, Faculty of Pharmacy, Comenius University in Bratislava, Odbojárov 10, 832 32 Bratislava, Slovak Republic. mikus@fpharm.uniba.sk.
Rauová D; Department of Pharmaceutical Analysis and Nuclear Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Odbojárov 10, 832 32 Bratislava, Slovak Republic. pecher1@uniba.sk.
Horváth C; Toxicological and Antidoping Center, Faculty of Pharmacy, Comenius University in Bratislava, Odbojárov 10, 832 32 Bratislava, Slovak Republic. pecher1@uniba.sk.
Szobi A; Department of Pharmaceutical Analysis and Nuclear Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Odbojárov 10, 832 32 Bratislava, Slovak Republic. rauova@fpharm.uniba.sk.
Adameová A; Toxicological and Antidoping Center, Faculty of Pharmacy, Comenius University in Bratislava, Odbojárov 10, 832 32 Bratislava, Slovak Republic. rauova@fpharm.uniba.sk.

Molecules ; 23(8)2018 Aug 03.

Article em En | MEDLINE | ID: mdl-30081531

Assuntos

Imidazóis/sangue; Indóis/sangue; Animais; Morte Celular/efeitos dos fármacos; Cromatografia Líquida de Alta Pressão; Relação Dose-Resposta a Droga; Humanos; Limite de Detecção; Masculino; Espectrometria de Massas; Ratos Wistar; Reprodutibilidade dos Testes

Palavras-chave

biomedical analysis; determination; high performance liquid chromatography; necrostatin Nec-1s; quadrupole-time-of-flight mass spectrometry; rat plasma

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imidazóis / Indóis Tipo de estudo: Guideline Limite: Animals / Humans / Male Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2018 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google