The LeuT-fold neurotransmitter:sodium symporter MhsT has two substrate sites.

Quick, Matthias; Abramyan, Ara M; Wiriyasermkul, Pattama; Weinstein, Harel; Shi, Lei; Javitch, Jonathan A

Quick, Matthias; Abramyan, Ara M; Wiriyasermkul, Pattama; Weinstein, Harel; Shi, Lei; Javitch, Jonathan A.

Afiliação

Quick M; Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY 10032; mq2102@cumc.columbia.edu Jonathan.Javitch@nyspi.columbia.edu.
Abramyan AM; Center for Molecular Recognition, Columbia University College of Physicians and Surgeons, New York, NY 10032.
Wiriyasermkul P; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY 10032.
Weinstein H; Computational Chemistry and Molecular Biophysics Unit, Molecular Targets and Medications Discovery Branch, NIH/National Institute on Drug Abuse/Intramural Research Program, Baltimore, MD 21224.
Shi L; Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY 10032.
Javitch JA; Department of Physiology and Biophysics and Institute for Computational Biomedicine, Weill Cornell Medical College of Cornell University, New York, NY 10065.

Proc Natl Acad Sci U S A ; 115(34): E7924-E7931, 2018 08 21.

Article em En | MEDLINE | ID: mdl-30082383

Assuntos

Proteínas de Bactérias/química; Lactococcus lactis/química; Simportadores/química; Cristalografia por Raios X; Humanos; Domínios Proteicos

Palavras-chave

LeuT fold; MhsT; membrane transport; neurotransmitter:sodium symporter

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Lactococcus lactis / Simportadores Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article

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