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An overview of meningiomas.
Buerki, Robin A; Horbinski, Craig M; Kruser, Timothy; Horowitz, Peleg M; James, Charles David; Lukas, Rimas V.
Afiliação
  • Buerki RA; Department of Neurological Surgery, University of California San Francisco, 400 Parnassus Ave., San Francisco, CA 94143, USA.
  • Horbinski CM; Department of Pathology, Northwestern University, IL 60611, USA.
  • Kruser T; Lou & Jean Malnati Brain Tumor Institute at the Lurie Comprehensive Cancer Center, Northwestern University, IL 60611, USA.
  • Horowitz PM; Lou & Jean Malnati Brain Tumor Institute at the Lurie Comprehensive Cancer Center, Northwestern University, IL 60611, USA.
  • James CD; Department of Radiation Oncology, Northwestern University, IL 60611, USA.
  • Lukas RV; Section of Neurosurgery, University of Chicago, 5841 S. Maryland Ave., Chicago, IL 60637, USA.
Future Oncol ; 14(21): 2161-2177, 2018 09.
Article em En | MEDLINE | ID: mdl-30084265
Meningiomas are the most common primary intracranial tumor. Important advances are occurring in meningioma research. These are expected to accelerate, potentially leading to impactful changes on the management of meningiomas in the near and medium term. This review will cover the histo- and molecular pathology of meningiomas, including recent 2016 updates to the WHO classification of CNS tumors. We will discuss clinical and radiographic presentation and therapeutic management. Surgery and radiotherapy, the two longstanding primary therapeutic modalities, will be discussed at length. In addition, data from prior and ongoing investigations of other treatment modalities, including systemic and targeted therapies, will be covered. This review will quickly update the reader on the contemporary management and future directions in meningiomas. [Formula: see text].
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Meníngeas / Meningioma Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Future Oncol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Meníngeas / Meningioma Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Future Oncol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos