Bacterial Protein Reshapes Host Defense toward Antiviral Responses.

Eoh, Hyungjin; Jung, Jae U

Eoh, Hyungjin; Jung, Jae U.

Afiliação

Eoh H; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA. Electronic address: heoh@usc.edu.
Jung JU; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

Mol Cell ; 71(4): 483-484, 2018 08 16.

Article em En | MEDLINE | ID: mdl-30118676

ABSTRACT

ABSTRACT

In this issue of Molecular Cell, Penn et al. (2018) report the protein interactome between Mycobacterium tuberculosis (Mtb) secreted effectors and macrophage cytosolic proteins. This Resource reveals that the interaction of Mtb effector LpqN with host CBL counteracts antibacterial defense but causes a reciprocal enhancement of antiviral defense.

Assuntos

Antivirais; Mycobacterium tuberculosis; Antibacterianos; Proteínas de Bactérias; Humanos; Macrófagos; Mapas de Interação de Proteínas

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Mycobacterium tuberculosis Limite: Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2018 Tipo de documento: Article

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