Heterogeneity and Coexistence of T790M and T790 Wild-Type Resistant Subclones Drive Mixed Response to Third-Generation Epidermal Growth Factor Receptor Inhibitors in Lung Cancer.

Piotrowska, Zofia; Hazar-Rethinam, Mehlika; Rizzo, Coleen; Nadres, Brandon; Van Seventer, Emily E; Shahzade, Heather A; Lennes, Inga T; Iafrate, Anthony J; Dias-Santagata, Dora; Leshchiner, Ignaty; Jessop, Nicholas A; Hu, Haichuan; Digumarthy, Subba R; Nagy, Rebecca J; Lanman, Richard B; Moody, Susan; Niederst, Matthew J; Engelman, Jeffrey A; Hata, Aaron N; Corcoran, Ryan B; Sequist, Lecia V

Piotrowska, Zofia; Hazar-Rethinam, Mehlika; Rizzo, Coleen; Nadres, Brandon; Van Seventer, Emily E; Shahzade, Heather A; Lennes, Inga T; Iafrate, Anthony J; Dias-Santagata, Dora; Leshchiner, Ignaty; Jessop, Nicholas A; Hu, Haichuan; Digumarthy, Subba R; Nagy, Rebecca J; Lanman, Richard B; Moody, Susan; Niederst, Matthew J; Engelman, Jeffrey A; Hata, Aaron N; Corcoran, Ryan B; Sequist, Lecia V.

Afiliação

Piotrowska Z; Massachusetts General Hospital, Boston.
Hazar-Rethinam M; Massachusetts General Hospital, Boston.
Rizzo C; Massachusetts General Hospital, Boston.
Nadres B; Massachusetts General Hospital, Boston.
Van Seventer EE; Massachusetts General Hospital, Boston.
Shahzade HA; Massachusetts General Hospital, Boston.
Lennes IT; Massachusetts General Hospital, Boston.
Iafrate AJ; Massachusetts General Hospital, Boston.
Dias-Santagata D; Massachusetts General Hospital, Boston.
Leshchiner I; Eli and Edythe L. Broad Institute of MIT and Harvard.
Jessop NA; Massachusetts General Hospital, Boston.
Hu H; Massachusetts General Hospital, Boston.
Digumarthy SR; Massachusetts General Hospital, Boston.
Nagy RJ; Guardant Health, Redwood City, CA.
Lanman RB; Guardant Health, Redwood City, CA.
Moody S; Novartis Institutes for Biomedical Research, Cambridge, MA.
Niederst MJ; Novartis Institutes for Biomedical Research, Cambridge, MA.
Engelman JA; Novartis Institutes for Biomedical Research, Cambridge, MA.
Hata AN; Massachusetts General Hospital, Boston.
Corcoran RB; Massachusetts General Hospital, Boston.
Sequist LV; Massachusetts General Hospital, Boston.

JCO Precis Oncol ; 20182018.

Article em En | MEDLINE | ID: mdl-30123863

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: JCO Precis Oncol Ano de publicação: 2018 Tipo de documento: Article

Texto completo

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XML

PubMed Links

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: JCO Precis Oncol Ano de publicação: 2018 Tipo de documento: Article