Molecular characterization of fluoroquinolones, macrolides, and imipenem resistance in Haemophilus influenzae: analysis of the mutations in QRDRs and assessment of the extent of the AcrAB-TolC-mediated resistance.

Cherkaoui, Abdessalam; Gaïa, Nadia; Baud, Damien; Leo, Stefano; Fischer, Adrien; Ruppe, Etienne; François, Patrice; Schrenzel, Jacques

Cherkaoui, Abdessalam; Gaïa, Nadia; Baud, Damien; Leo, Stefano; Fischer, Adrien; Ruppe, Etienne; François, Patrice; Schrenzel, Jacques.

Afiliação

Cherkaoui A; Bacteriology Laboratory, Service of Laboratory Medicine, Department of Genetics, Laboratory Medicine and Pathology, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, 1205, Geneva, Switzerland. abdessalam.cherkaoui@hcuge.ch.
Gaïa N; Genomic Research Laboratory, Division of Infectious Diseases, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, 1205, Geneva, Switzerland.
Baud D; Genomic Research Laboratory, Division of Infectious Diseases, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, 1205, Geneva, Switzerland.
Leo S; Genomic Research Laboratory, Division of Infectious Diseases, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, 1205, Geneva, Switzerland.
Fischer A; Bacteriology Laboratory, Service of Laboratory Medicine, Department of Genetics, Laboratory Medicine and Pathology, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, 1205, Geneva, Switzerland.
Ruppe E; AP-HP, Hôpital Bichat, Laboratoire de Bactériologie, INSERM, IAME, UMR 1137, Université Paris Diderot, IAME, UMR 1137, Sorbonne Paris Cité, 75018, Paris, France.
François P; Genomic Research Laboratory, Division of Infectious Diseases, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, 1205, Geneva, Switzerland.
Schrenzel J; Bacteriology Laboratory, Service of Laboratory Medicine, Department of Genetics, Laboratory Medicine and Pathology, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, 1205, Geneva, Switzerland.

Eur J Clin Microbiol Infect Dis ; 37(11): 2201-2210, 2018 Nov.

Article em En | MEDLINE | ID: mdl-30145620

Assuntos

Fluoroquinolonas/farmacologia; Infecções por Haemophilus/microbiologia; Haemophilus influenzae/efeitos dos fármacos; Haemophilus influenzae/genética; Imipenem/farmacologia; Macrolídeos/farmacologia; Adulto; Idoso; Antibacterianos/farmacologia; Proteínas de Bactérias/genética; Proteínas de Bactérias/metabolismo; Feminino; Genoma Bacteriano; Genômica/métodos; Haemophilus influenzae/classificação; Humanos; Masculino; Testes de Sensibilidade Microbiana; Pessoa de Meia-Idade; Tipagem de Sequências Multilocus; Mutação; Sorogrupo; Sequenciamento Completo do Genoma

Palavras-chave

Antibiotic resistance; CCCP; Fluoroquinolone; H. influenzae; Imipenem; Macrolide; Whole-genome sequencing; cgMLST

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imipenem / Haemophilus influenzae / Macrolídeos / Fluoroquinolonas / Infecções por Haemophilus Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Clin Microbiol Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS / MICROBIOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suíça

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