Preferential Binding of Mg<sup>2+</sup> Over Ca<sup>2+</sup> to CIB2 Triggers an Allosteric Switch Impaired in Usher Syndrome Type 1J.

Vallone, Rosario; Dal Cortivo, Giuditta; D'Onofrio, Mariapina; Dell'Orco, Daniele

Preferential Binding of Mg²⁺ Over Ca²⁺ to CIB2 Triggers an Allosteric Switch Impaired in Usher Syndrome Type 1J.

Vallone, Rosario; Dal Cortivo, Giuditta; D'Onofrio, Mariapina; Dell'Orco, Daniele.

Afiliação

Vallone R; Section of Biological Chemistry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Dal Cortivo G; Section of Biological Chemistry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
D'Onofrio M; Department of Biotechnology, University of Verona, Verona Italy.
Dell'Orco D; Section of Biological Chemistry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.

Front Mol Neurosci ; 11: 274, 2018.

Article em En | MEDLINE | ID: mdl-30174586

Palavras-chave

DFNB48; Usher syndrome 1J; allostery; calcium and integrin binding protein; calcium sensor; hearing loss; magnesium; nuclear magnetic resonance

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Mol Neurosci Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Itália

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