Affibody-Based PET Imaging to Guide EGFR-Targeted Cancer Therapy in Head and Neck Squamous Cell Cancer Models.

Burley, Thomas A; Da Pieve, Chiara; Martins, Carlos D; Ciobota, Daniela M; Allott, Louis; Oyen, Wim J G; Harrington, Kevin J; Smith, Graham; Kramer-Marek, Gabriela

Burley, Thomas A; Da Pieve, Chiara; Martins, Carlos D; Ciobota, Daniela M; Allott, Louis; Oyen, Wim J G; Harrington, Kevin J; Smith, Graham; Kramer-Marek, Gabriela.

Afiliação

Burley TA; Division of Radiotherapy and Imaging, Institute of Cancer Research, London, United Kingdom; and.
Da Pieve C; Division of Radiotherapy and Imaging, Institute of Cancer Research, London, United Kingdom; and.
Martins CD; Division of Radiotherapy and Imaging, Institute of Cancer Research, London, United Kingdom; and.
Ciobota DM; Division of Radiotherapy and Imaging, Institute of Cancer Research, London, United Kingdom; and.
Allott L; Division of Radiotherapy and Imaging, Institute of Cancer Research, London, United Kingdom; and.
Oyen WJG; Division of Radiotherapy and Imaging, Institute of Cancer Research, London, United Kingdom; and.
Harrington KJ; Department of Nuclear Medicine, Royal Marsden NHS Foundation Trust, London, United Kingdom.
Smith G; Division of Radiotherapy and Imaging, Institute of Cancer Research, London, United Kingdom; and.
Kramer-Marek G; Division of Radiotherapy and Imaging, Institute of Cancer Research, London, United Kingdom; and.

J Nucl Med ; 60(3): 353-361, 2019 03.

Article em En | MEDLINE | ID: mdl-30213849

Assuntos

Cetuximab/uso terapêutico; Terapia de Alvo Molecular; Carcinoma de Células Escamosas de Cabeça e Pescoço/diagnóstico por imagem; Carcinoma de Células Escamosas de Cabeça e Pescoço/tratamento farmacológico; Animais; Linhagem Celular Tumoral; Cetuximab/metabolismo; Cetuximab/farmacocinética; Regulação para Baixo; Receptores ErbB/metabolismo; Humanos; Camundongos; Radioisótopos/uso terapêutico; Carcinoma de Células Escamosas de Cabeça e Pescoço/imunologia; Carcinoma de Células Escamosas de Cabeça e Pescoço/metabolismo; Distribuição Tecidual; Zircônio/uso terapêutico

Palavras-chave

18F; 89Zr; Affibody molecules; EGFR; cancer imaging

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia de Alvo Molecular / Cetuximab / Carcinoma de Células Escamosas de Cabeça e Pescoço Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Nucl Med Ano de publicação: 2019 Tipo de documento: Article

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