Upregulation of 24(R/S),25-epoxycholesterol and 27-hydroxycholesterol suppresses the proliferation and migration of gastric cancer cells.

Guo, Fenghua; Hong, Wenting; Yang, Mingjie; Xu, Dongke; Bai, Qianming; Li, Xiaobo; Chen, Zongyou

Guo, Fenghua; Hong, Wenting; Yang, Mingjie; Xu, Dongke; Bai, Qianming; Li, Xiaobo; Chen, Zongyou.

Afiliação

Guo F; Department of General Surgery, Hua'shan Hospital, Fudan University Shanghai Medical College, Shanghai, China.
Hong W; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Yang M; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Xu D; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Bai Q; Department of Pathology, Fudan University Shanghai Cancer Centre, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Li X; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, China. Electronic address: xbli@fudan.edu.cn.
Chen Z; Department of General Surgery, Hua'shan Hospital, Fudan University Shanghai Medical College, Shanghai, China. Electronic address: zongyouchen@hotmail.com.

Biochem Biophys Res Commun ; 504(4): 892-898, 2018 10 12.

Article em En | MEDLINE | ID: mdl-30224060

Assuntos

Colesterol/análogos & derivados; Hidroxicolesteróis/metabolismo; Neoplasias Gástricas/metabolismo; Neoplasias Gástricas/patologia; Estudos de Casos e Controles; Movimento Celular/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Colesterol/metabolismo; Colesterol/farmacologia; Suco Gástrico/metabolismo; Mucosa Gástrica/metabolismo; Mucosa Gástrica/patologia; Perfilação da Expressão Gênica; Humanos; Hidroxicolesteróis/farmacologia; Receptores X do Fígado/genética; Receptores X do Fígado/metabolismo; Oxisteróis/metabolismo; Neoplasias Gástricas/tratamento farmacológico; Neoplasias Gástricas/genética; Sulfotransferases/genética; Sulfotransferases/metabolismo; Regulação para Cima

Palavras-chave

24(R/S),25-epoxycholesterol; 27-Hydroxycholesterol; Gastric cancer; Oxysterols

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Colesterol / Hidroxicolesteróis Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China

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