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Systems biology approach reveals a link between mTORC1 and G2/M DNA damage checkpoint recovery.
Hsieh, Hui-Ju; Zhang, Wei; Lin, Shu-Hong; Yang, Wen-Hao; Wang, Jun-Zhong; Shen, Jianfeng; Zhang, Yiran; Lu, Yiling; Wang, Hua; Yu, Jane; Mills, Gordon B; Peng, Guang.
Afiliação
  • Hsieh HJ; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Zhang W; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Lin SH; QIAGEN (Suzhou) Translational Medicine Co., Ltd, Jiangsu Province, 215123, China.
  • Yang WH; Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Wang JZ; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Shen J; Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, Guangdong Province, 510095, China.
  • Zhang Y; Department of Electrical Engineering, National Kaohsiung University of Applied Sciences, Kaohsiung, 80778, Taiwan.
  • Lu Y; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Wang H; Department of Mathematical Sciences, Georgia Southern University, Statesboro, GA, 30460, USA.
  • Yu J; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Mills GB; Department of Mathematical Sciences, Georgia Southern University, Statesboro, GA, 30460, USA.
  • Peng G; Division of Pulmonary, Critical Care, and Sleep Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA.
Nat Commun ; 9(1): 3982, 2018 09 28.
Article em En | MEDLINE | ID: mdl-30266942

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Biologia de Sistemas / Reparo do DNA / Pontos de Checagem da Fase G2 do Ciclo Celular / Alvo Mecanístico do Complexo 1 de Rapamicina Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Biologia de Sistemas / Reparo do DNA / Pontos de Checagem da Fase G2 do Ciclo Celular / Alvo Mecanístico do Complexo 1 de Rapamicina Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos