Hepatic Expression of PEMT, but Not Dietary Choline Supplementation, Reverses the Protection against Atherosclerosis in Pemt-/-/Ldlr-/- Mice.

Zia, Yumna; Al Rajabi, Ala; Mi, Si; Ju, Tingting; Leonard, Kelly-Ann; Nelson, Randal; Thiesen, Aducio; Willing, Benjamin P; Field, Catherine J; Curtis, Jonathan M; van der Veen, Jelske N; Jacobs, René L

Zia, Yumna; Al Rajabi, Ala; Mi, Si; Ju, Tingting; Leonard, Kelly-Ann; Nelson, Randal; Thiesen, Aducio; Willing, Benjamin P; Field, Catherine J; Curtis, Jonathan M; van der Veen, Jelske N; Jacobs, René L.

Afiliação

Zia Y; Departments of Agricultural, Food, and Nutritional Science.
Al Rajabi A; Departments of Agricultural, Food, and Nutritional Science.
Mi S; Departments of Agricultural, Food, and Nutritional Science.
Ju T; Departments of Agricultural, Food, and Nutritional Science.
Leonard KA; Departments of Agricultural, Food, and Nutritional Science.
Nelson R; Biochemistry.
Thiesen A; Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada.
Willing BP; Departments of Agricultural, Food, and Nutritional Science.
Field CJ; Departments of Agricultural, Food, and Nutritional Science.
Curtis JM; Departments of Agricultural, Food, and Nutritional Science.
van der Veen JN; Biochemistry.
Jacobs RL; Departments of Agricultural, Food, and Nutritional Science.

J Nutr ; 148(10): 1513-1520, 2018 10 01.

Article em En | MEDLINE | ID: mdl-30281112

Assuntos

Aterosclerose/metabolismo; Colesterol/sangue; Colina/farmacologia; Fígado/metabolismo; Metilaminas/sangue; Fosfatidiletanolamina N-Metiltransferase/metabolismo; Receptores de LDL/metabolismo; Animais; Aorta; Aterosclerose/etiologia; Aterosclerose/patologia; Aterosclerose/prevenção & controle; Colesterol na Dieta/administração & dosagem; Colina/metabolismo; Dieta Ocidental; Suplementos Nutricionais; Humanos; Masculino; Camundongos Endogâmicos C57BL; Camundongos Knockout; Fosfatidiletanolamina N-Metiltransferase/farmacologia; Fosfatidiletanolaminas/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de LDL / Colesterol / Colina / Aterosclerose / Fosfatidiletanolamina N-Metiltransferase / Fígado / Metilaminas Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Revista: J Nutr Ano de publicação: 2018 Tipo de documento: Article

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