The 3D Genome Browser: a web-based browser for visualizing 3D genome organization and long-range chromatin interactions.
Genome Biol
; 19(1): 151, 2018 10 04.
Article
em En
| MEDLINE
| ID: mdl-30286773
ABSTRACT
Here, we introduce the 3D Genome Browser, http//3dgenome.org , which allows users to conveniently explore both their own and over 300 publicly available chromatin interaction data of different types. We design a new binary data format for Hi-C data that reduces the file size by at least a magnitude and allows users to visualize chromatin interactions over millions of base pairs within seconds. Our browser provides multiple methods linking distal cis-regulatory elements with their potential target genes. Users can seamlessly integrate thousands of other omics data to gain a comprehensive view of both regulatory landscape and 3D genome structure.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cromatina
/
Genoma Humano
/
Imageamento Tridimensional
/
Navegador
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Genome Biol
Assunto da revista:
BIOLOGIA MOLECULAR
/
GENETICA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Estados Unidos