Locally optimal designs for some binary dose-response models.
Can J Stat
; 46(2): 336-354, 2018 Jun.
Article
em En
| MEDLINE
| ID: mdl-30287980
ABSTRACT
In this paper, we consider the problem of seeking locally optimal designs for nonlinear dose-response models with binary outcomes. Applying the theory of Tchebycheff Systems and other algebraic tools, we show that the locally D-, A-, and c-optimal designs for three binary dose-response models are minimally supported in finite, closed design intervals. The methods to obtain such designs are presented along with examples. The efficiencies of these designs are also discussed.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Can J Stat
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
China