Episomal expression of human glutathione reductase (HuGR) in Leishmania sheds light on evolutionary pressure for unique redox metabolism pathway: Impaired stress tolerance ability of Leishmania donovani.

Prakash, Jay; Yadav, Sunita; Saha, Gundappa; Chiranjivi, Adarsh Kumar; Kumar, Suresh; Sasidharan, Santanu; Saudagar, Prakash; Dubey, Vikash Kumar

Prakash, Jay; Yadav, Sunita; Saha, Gundappa; Chiranjivi, Adarsh Kumar; Kumar, Suresh; Sasidharan, Santanu; Saudagar, Prakash; Dubey, Vikash Kumar.

Afiliação

Prakash J; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India.
Yadav S; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India; School of Biochemical Engineering, Indian Institute of Technology (BHU) Varanasi, Varanasi 221005, India.
Saha G; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India.
Chiranjivi AK; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India.
Kumar S; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India.
Sasidharan S; Department of Biotechnology, National Institute of Technology, Warangal 506004, India.
Saudagar P; Department of Biotechnology, National Institute of Technology, Warangal 506004, India. Electronic address: ps@nitw.ac.in.
Dubey VK; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India; School of Biochemical Engineering, Indian Institute of Technology (BHU) Varanasi, Varanasi 221005, India. Electronic address: vkdubey.bce@iitbhu.ac.in.

Int J Biol Macromol ; 121: 498-507, 2019 Jan.

Article em En | MEDLINE | ID: mdl-30316767

Assuntos

Evolução Molecular; Regulação Enzimológica da Expressão Gênica; Glutationa Redutase/metabolismo; Leishmania donovani/metabolismo; Plasmídeos/metabolismo; Estresse Fisiológico; Linhagem Celular; Humanos; Espaço Intracelular/metabolismo; Espaço Intracelular/parasitologia; Leishmania donovani/enzimologia; Leishmania donovani/fisiologia; Oxirredução; Espécies Reativas de Oxigênio/metabolismo; Compostos de Sulfidrila/metabolismo

Palavras-chave

Glutathione reductase; Leishmania; Redox metabolism

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmídeos / Estresse Fisiológico / Leishmania donovani / Regulação Enzimológica da Expressão Gênica / Evolução Molecular / Glutationa Redutase Limite: Humans Idioma: En Revista: Int J Biol Macromol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Índia

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