Fluorescence-guided surgery with aminolevulinic acid for low-grade gliomas.
J Neurooncol
; 141(1): 13-18, 2019 Jan.
Article
em En
| MEDLINE
| ID: mdl-30367383
ABSTRACT
INTRODUCTION:
Fluorescence guided surgery has developed over the last 2 decades as a formidable augmentation strategy to promote maximal safe resection and diagnostic accuracy within gliomas. The majority of the literature evidence supporting this modality utilizes 5-aminolevulinic acid in the setting of high-grade gliomas. The role for fluorescence guided surgery in low-grade gliomas is less well defined.RESULTS:
This review describes the existing literature discussing the utilization of 5-aminolevulinic acid for fluorescence guided surgery in low-grade gliomas, including its pertinence in identification of anaplastic foci and potential role in guiding resection following combination with augmentation strategies for detection.CONCLUSION:
The advance in operative technology and growth of research analyzing 5-aminolevulinic acid will continue to enhance the role of fluorescence guided surgery within the standard of surgical management for low-grade gliomas.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Encefálicas
/
Neuronavegação
/
Glioma
/
Ácido Aminolevulínico
/
Microscopia de Fluorescência
Limite:
Humans
Idioma:
En
Revista:
J Neurooncol
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Estados Unidos