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Is low dose radiotherapy an effective treatment for Baker's cyst?
Hautmann, Matthias G; Jung, Ernst-Michael; Beyer, Lukas P; Süß, Christoph; Steger, Felix; Weber, Markus; Pohl, Fabian; Kölbl, Oliver; Putz, Franz Josef.
Afiliação
  • Hautmann MG; Department of Radiotherapy, University of Regensburg, Regensburg, Germany. matthias.hautmann@ukr.de.
  • Jung EM; Department of Radiology, University of Regensburg, Regensburg, Germany.
  • Beyer LP; Department of Radiology, University of Regensburg, Regensburg, Germany.
  • Süß C; Department of Radiotherapy, University of Regensburg, Regensburg, Germany.
  • Steger F; Department of Radiotherapy, University of Regensburg, Regensburg, Germany.
  • Weber M; Department of Orthopaedics, Asklepios Klinikum Bad Abbach, University of Regensburg, Bad Abbach, Germany.
  • Pohl F; Department of Radiotherapy, University of Regensburg, Regensburg, Germany.
  • Kölbl O; Department of Radiotherapy, University of Regensburg, Regensburg, Germany.
  • Putz FJ; Department of Nephrology, University of Regensburg, Regensburg, Germany.
Strahlenther Onkol ; 195(1): 69-76, 2019 Jan.
Article em En | MEDLINE | ID: mdl-30377698
ABSTRACT

PURPOSE:

Osteoarthritis of the knee is a common disease, often associated with a Baker's cyst. Besides osteoarthritis, also other joint pathologies of the knee can be causative for a Baker's cyst. Radiotherapy is known to be an effective treatment for osteoarthritis, with an anti-inflammatory effect. As the excessive production of synovia usually is associated with intraarticular inflammation, our hypothesis was that radiotherapy might positively influence the synovial production and reduce the volume of a Baker's cyst. MATERIALS AND

METHODS:

We performed a prospective trial, including 20 knees receiving radiotherapy for knee arthritis. Besides documentation of NRS (numeric rating scale), WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) score and Knee Society Score, the volume of the Baker's cyst was calculated for a short- (6 to 12 weeks) and long-term (9 to 12 months) follow-up. Ultrasonic volumetry was performed using an ultrasound device with a high-resolution multifrequency linear probe (6-9 MHz).

RESULTS:

Low-dose radiotherapy improved NRS, WOMAC score and Knee Society Score significantly. The mean volume of Baker's cyst decreased from 22.3 ml to 10.7 respectively 3.1 ml during follow-up. A decrease in volume of more than 25% compared to the baseline could be achieved for 75% of the patients in the short-term and 79% of the patients in the long-term follow up.

CONCLUSION:

Radiotherapy of knee osteoarthritis is an effective treatment that decreases the volume of a Baker's cyst. Most patients respond to the treatment. Whether radiotherapy is an effective treatment for Baker's cyst without associated osteoarthritis has to be further examined.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dosagem Radioterapêutica / Cisto Popliteal / Osteoartrite do Joelho Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Strahlenther Onkol Assunto da revista: NEOPLASIAS / RADIOTERAPIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dosagem Radioterapêutica / Cisto Popliteal / Osteoartrite do Joelho Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Strahlenther Onkol Assunto da revista: NEOPLASIAS / RADIOTERAPIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha