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Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models.
Zakharenko, A L; Luzina, O A; Sokolov, D N; Kaledin, V I; Nikolin, V P; Popova, N A; Patel, J; Zakharova, O D; Chepanova, A A; Zafar, A; Reynisson, J; Leung, E; Leung, I K H; Volcho, K P; Salakhutdinov, N F; Lavrik, O I.
Afiliação
  • Zakharenko AL; Novosibirsk Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 8, Akademika Lavrentieva Ave., Novosibirsk, 630090, Russian Federation.
  • Luzina OA; N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9, Akademika Lavrentieva Ave., Novosibirsk, 630090, Russian Federation.
  • Sokolov DN; N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9, Akademika Lavrentieva Ave., Novosibirsk, 630090, Russian Federation.
  • Kaledin VI; Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, 10, Akademika Lavrentieva Ave., Novosibirsk, 630090, Russian Federation.
  • Nikolin VP; Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, 10, Akademika Lavrentieva Ave., Novosibirsk, 630090, Russian Federation.
  • Popova NA; Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, 10, Akademika Lavrentieva Ave., Novosibirsk, 630090, Russian Federation; Novosibirsk State University, Pirogova str. 1, Novosibirsk, 630090, Russian Federation.
  • Patel J; School of Chemical Sciences, The University of Auckland, New Zealand.
  • Zakharova OD; Novosibirsk Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 8, Akademika Lavrentieva Ave., Novosibirsk, 630090, Russian Federation.
  • Chepanova AA; Novosibirsk Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 8, Akademika Lavrentieva Ave., Novosibirsk, 630090, Russian Federation.
  • Zafar A; School of Chemical Sciences, The University of Auckland, New Zealand.
  • Reynisson J; School of Chemical Sciences, The University of Auckland, New Zealand.
  • Leung E; Auckland Cancer Society Research Centre and Department of Molecular Medicine and Pathology, The University of Auckland, New Zealand.
  • Leung IKH; School of Chemical Sciences, The University of Auckland, New Zealand.
  • Volcho KP; N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9, Akademika Lavrentieva Ave., Novosibirsk, 630090, Russian Federation; Novosibirsk State University, Pirogova str. 1, Novosibirsk, 630090, Russian Federation.
  • Salakhutdinov NF; N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9, Akademika Lavrentieva Ave., Novosibirsk, 630090, Russian Federation; Novosibirsk State University, Pirogova str. 1, Novosibirsk, 630090, Russian Federation.
  • Lavrik OI; Novosibirsk Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 8, Akademika Lavrentieva Ave., Novosibirsk, 630090, Russian Federation; Novosibirsk State University, Pirogova str. 1, Novosibirsk, 630090, Russian Federation. Electronic address:
Eur J Med Chem ; 161: 581-593, 2019 Jan 01.
Article em En | MEDLINE | ID: mdl-30396105
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diester Fosfórico Hidrolases / Topotecan / Inibidores da Topoisomerase I / Neoplasias Pulmonares / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diester Fosfórico Hidrolases / Topotecan / Inibidores da Topoisomerase I / Neoplasias Pulmonares / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2019 Tipo de documento: Article