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Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 2: Fed State.
Paixão, Paulo; Bermejo, Marival; Hens, Bart; Tsume, Yasuhiro; Dickens, Joseph; Shedden, Kerby; Salehi, Niloufar; Koenigsknecht, Mark J; Baker, Jason R; Hasler, William L; Lionberger, Robert; Fan, Jianghong; Wysocki, Jeffrey; Wen, Bo; Lee, Allen; Frances, Ann; Amidon, Gregory E; Yu, Alex; Benninghoff, Gail; Löbenberg, Raimar; Talattof, Arjang; Sun, Duxin; Amidon, Gordon L.
Afiliação
  • Paixão P; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Bermejo M; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy , Universidade de Lisboa , Avenida Professor Gama Pinto , 1649-003 Lisboa , Portugal.
  • Hens B; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Tsume Y; Department of Engineering, Pharmacy Section , Miguel Hernandez University , San Juan de Alicante, 03550 Alicante , Spain.
  • Dickens J; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Shedden K; Department of Pharmaceutical and Pharmacological Sciences , KU Leuven , Herestraat 49 , 3000 Leuven , Belgium.
  • Salehi N; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Hasler WL; Center for the Study of Complex Systems and Department of Chemical Engineering , University of Michigan , Ann Arbor , Michigan 48109-2136 , United States.
  • Lionberger R; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Fan J; Department of Internal Medicine, Division of Gastroenterology , University of Michigan , Ann Arbor , Michigan 48109 , United States.
  • Wysocki J; Department of Internal Medicine, Division of Gastroenterology , University of Michigan , Ann Arbor , Michigan 48109 , United States.
  • Wen B; Office of Generic Drugs, Center for Drug Evaluation and Research , U.S. Food and Drug Administration , Silver Spring , Maryland 20993 , United States.
  • Lee A; Office of Generic Drugs, Center for Drug Evaluation and Research , U.S. Food and Drug Administration , Silver Spring , Maryland 20993 , United States.
  • Frances A; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Amidon GE; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Yu A; Department of Internal Medicine, Division of Gastroenterology , University of Michigan , Ann Arbor , Michigan 48109 , United States.
  • Benninghoff G; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Löbenberg R; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Talattof A; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Sun D; Department of Pharmaceutical Sciences, College of Pharmacy , University of Michigan , 428 Church Street , Ann Arbor , Michigan 48109-1065 , United States.
  • Amidon GL; Faculty of Pharmacy & Pharmaceutical Sciences , University of Alberta , Edmonton , Alberta , Canada T6G 2H7.
Mol Pharm ; 15(12): 5468-5478, 2018 12 03.
Article em En | MEDLINE | ID: mdl-30417648
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estômago / Ibuprofeno / Período Pós-Prandial / Liberação Controlada de Fármacos / Absorção Gástrica Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estômago / Ibuprofeno / Período Pós-Prandial / Liberação Controlada de Fármacos / Absorção Gástrica Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos