The intron 3 16 bp duplication polymorphism of p53 (rs17878362) is not associated with increased risk of developing triple-negative breast cancer.

Morten, Brianna C; Chiu, Simon; Oldmeadow, Christopher; Lubinski, Jan; Scott, Rodney J; Avery-Kiejda, Kelly A

The intron 3 16 bp duplication polymorphism of p53 (rs17878362) is not associated with increased risk of developing triple-negative breast cancer.

Morten, Brianna C; Chiu, Simon; Oldmeadow, Christopher; Lubinski, Jan; Scott, Rodney J; Avery-Kiejda, Kelly A.

Afiliação

Morten BC; Centre for Information Based Medicine, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.
Chiu S; Priority Research Centre for Cancer Research, Innovation and Translation, School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, Callaghan, NSW, Australia.
Oldmeadow C; CREDITSS-Clinical Research Design, Information Technology and Statistical Support Unit, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.
Lubinski J; CREDITSS-Clinical Research Design, Information Technology and Statistical Support Unit, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia.
Scott RJ; School of Medicine and Public Health, The University of Newcastle, Callaghan, NSW, Australia.
Avery-Kiejda KA; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.

Breast Cancer Res Treat ; 173(3): 727-733, 2019 Feb.

Article em En | MEDLINE | ID: mdl-30430302

Assuntos

Duplicação Gênica; Íntrons; Polimorfismo Genético; Sequências Repetitivas de Ácido Nucleico; Neoplasias de Mama Triplo Negativas/genética; Proteína Supressora de Tumor p53/genética; Idoso; Alelos; Feminino; Genótipo; Humanos; Pessoa de Meia-Idade; Estadiamento de Neoplasias; Razão de Chances; Fatores de Risco; Análise de Sobrevida; Neoplasias de Mama Triplo Negativas/mortalidade; Neoplasias de Mama Triplo Negativas/patologia

Palavras-chave

Breast cancer; Risk factor; TNBC; p53; rs17878362

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Íntrons / Sequências Repetitivas de Ácido Nucleico / Proteína Supressora de Tumor p53 / Duplicação Gênica / Neoplasias de Mama Triplo Negativas Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Aged / Female / Humans / Middle aged Idioma: En Revista: Breast Cancer Res Treat Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Austrália

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