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Measurable residual disease-guided treatment with azacitidine to prevent haematological relapse in patients with myelodysplastic syndrome and acute myeloid leukaemia (RELAZA2): an open-label, multicentre, phase 2 trial.
Platzbecker, Uwe; Middeke, Jan Moritz; Sockel, Katja; Herbst, Regina; Wolf, Dominik; Baldus, Claudia D; Oelschlägel, Uta; Mütherig, Anke; Fransecky, Lars; Noppeney, Richard; Bug, Gesine; Götze, Katharina S; Krämer, Alwin; Bochtler, Tilmann; Stelljes, Matthias; Groth, Christoph; Schubert, Antje; Mende, Marika; Stölzel, Friedrich; Borkmann, Christine; Kubasch, Anne Sophie; von Bonin, Malte; Serve, Hubert; Hänel, Mathias; Dührsen, Ulrich; Schetelig, Johannes; Röllig, Christoph; Kramer, Michael; Ehninger, Gerhard; Bornhäuser, Martin; Thiede, Christian.
Afiliação
  • Platzbecker U; Medical Clinic and Policinic 1, Hematology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany; Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases
  • Middeke JM; Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.
  • Sockel K; Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.
  • Herbst R; Klinikum Chemnitz, Klinik für Hämatologie und Onkologie, Chemnitz, Germany.
  • Wolf D; Medical Clinic 3, Universitätsklinikum Bonn, Bonn, Germany; UKIM5, Medical University Innsbruck, Innsbruck, Austria.
  • Baldus CD; Medizinische Klinik mit Schwerpunkt Hämatologie und Onkologie, Campus Benjamin Franklin Charité, Berlin, Germany.
  • Oelschlägel U; Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.
  • Mütherig A; Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.
  • Fransecky L; Medizinische Klinik mit Schwerpunkt Hämatologie und Onkologie, Campus Benjamin Franklin Charité, Berlin, Germany.
  • Noppeney R; Universitätsklinikum Essen, Klinik für Hämatologie, Essen, Germany.
  • Bug G; Universitätsklinikum Frankfurt, Medizinische Klinik 2, Universitätsklinikum Frankfurt, Frankfurt, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Frankfurt, Germany.
  • Götze KS; Technische Universität München, Munich, Germany.
  • Krämer A; Medizinische Klinik V, Universität Heidelberg and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Bochtler T; Medizinische Klinik V, Universität Heidelberg and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Stelljes M; Universitätsklinikum Münster, Medizinischen Klinik A, Münster, Germany.
  • Groth C; Universitätsklinikum Münster, Medizinischen Klinik A, Münster, Germany.
  • Schubert A; Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.
  • Mende M; Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.
  • Stölzel F; Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.
  • Borkmann C; Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.
  • Kubasch AS; Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.
  • von Bonin M; Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.
  • Serve H; Universitätsklinikum Frankfurt, Medizinische Klinik 2, Universitätsklinikum Frankfurt, Frankfurt, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Frankfurt, Germany.
  • Hänel M; Klinikum Chemnitz, Klinik für Hämatologie und Onkologie, Chemnitz, Germany.
  • Dührsen U; Universitätsklinikum Essen, Klinik für Hämatologie, Essen, Germany.
  • Schetelig J; Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.
  • Röllig C; Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.
  • Kramer M; Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.
  • Ehninger G; Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.
  • Bornhäuser M; Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.
  • Thiede C; Universitätsklinikum "Carl Gustav Carus" der Technischen Universität Dresden, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), and National Center for Tumor Diseases (NCT) Dresden, Dresden, Germany.
Lancet Oncol ; 19(12): 1668-1679, 2018 12.
Article em En | MEDLINE | ID: mdl-30442503
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Azacitidina / Síndromes Mielodisplásicas / Leucemia Mieloide Aguda / Antimetabólitos Antineoplásicos Tipo de estudo: Clinical_trials / Etiology_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: Lancet Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Azacitidina / Síndromes Mielodisplásicas / Leucemia Mieloide Aguda / Antimetabólitos Antineoplásicos Tipo de estudo: Clinical_trials / Etiology_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: Lancet Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article