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Loss of G9a preserves mutation patterns but increases chromatin accessibility, genomic instability and aggressiveness in skin tumours.
Avgustinova, Alexandra; Symeonidi, Aikaterini; Castellanos, Andrés; Urdiroz-Urricelqui, Uxue; Solé-Boldo, Llorenç; Martín, Mercè; Pérez-Rodríguez, Ivan; Prats, Neus; Lehner, Ben; Supek, Fran; Benitah, Salvador Aznar.
Afiliação
  • Avgustinova A; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. alexandra.avgustinova@irbbarcelona.org.
  • Symeonidi A; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
  • Castellanos A; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
  • Urdiroz-Urricelqui U; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
  • Solé-Boldo L; Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.
  • Martín M; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
  • Pérez-Rodríguez I; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
  • Prats N; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
  • Lehner B; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
  • Supek F; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain.
  • Benitah SA; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. fran.supek@irbbarcelona.org.
Nat Cell Biol ; 20(12): 1400-1409, 2018 12.
Article em En | MEDLINE | ID: mdl-30455462
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Cromatina / Histona-Lisina N-Metiltransferase / Instabilidade Genômica / Mutação Limite: Animals / Humans Idioma: En Revista: Nat Cell Biol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Espanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Cromatina / Histona-Lisina N-Metiltransferase / Instabilidade Genômica / Mutação Limite: Animals / Humans Idioma: En Revista: Nat Cell Biol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Espanha