Current landscape of immunotherapy in the treatment of solid tumours, with future opportunities and challenges.
Curr Oncol
; 25(5): e373-e384, 2018 10.
Article
em En
| MEDLINE
| ID: mdl-30464687
ABSTRACT
Immunotherapy has emerged as a new standard of care, showing survival benefit for solid tumours in multiple disease sites and indications. The survival improvements seen in diseases that were highly resistant to traditional therapies, with a poor prognosis, are unprecedented. Although the benefits observed in clinical trials are undeniable, not all patients derive those benefits, leading to emerging combination strategies and an ongoing quest for biomarker selection. Here, we summarize the current evidence for immunotherapy in the treatment of solid tumours, and we discuss emerging strategies at the forefront of research. We discuss future challenges that will be encountered as experience and knowledge continue to expand in this rapidly emerging field.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Antineoplásicos Imunológicos
/
Imunoterapia
/
Neoplasias
Limite:
Humans
Idioma:
En
Revista:
Curr Oncol
Ano de publicação:
2018
Tipo de documento:
Article