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ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the androgen axis.
Rotinen, Mirja; You, Sungyong; Yang, Julie; Coetzee, Simon G; Reis-Sobreiro, Mariana; Huang, Wen-Chin; Huang, Fangjin; Pan, Xinlei; Yáñez, Alberto; Hazelett, Dennis J; Chu, Chia-Yi; Steadman, Kenneth; Morrissey, Colm M; Nelson, Peter S; Corey, Eva; Chung, Leland W K; Freedland, Stephen J; Di Vizio, Dolores; Garraway, Isla P; Murali, Ramachandran; Knudsen, Beatrice S; Freeman, Michael R.
Afiliação
  • Rotinen M; Division of Cancer Biology and Therapeutics, Departments of Surgery & Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • You S; Division of Cancer Biology and Therapeutics, Departments of Surgery & Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Yang J; Division of Cancer Biology and Therapeutics, Departments of Surgery & Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Coetzee SG; The Center for Bioinformatics and Functional Genomics, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Reis-Sobreiro M; Division of Cancer Biology and Therapeutics, Departments of Surgery & Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Huang WC; Division of Cancer Biology and Therapeutics, Departments of Surgery & Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Huang F; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.
  • Pan X; Division of Cancer Biology and Therapeutics, Departments of Surgery & Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Yáñez A; Division of Immunology, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Hazelett DJ; Board of Governors Regenerative Medicine Institute and Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Chu CY; The Center for Bioinformatics and Functional Genomics, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Steadman K; Uro-Oncology Research Program, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Morrissey CM; Division of Cancer Biology and Therapeutics, Departments of Surgery & Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Nelson PS; Department of Urology, University of Washington, Seattle, WA, USA.
  • Corey E; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Chung LWK; Department of Urology, University of Washington, Seattle, WA, USA.
  • Freedland SJ; Uro-Oncology Research Program, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Di Vizio D; Division of Cancer Biology and Therapeutics, Departments of Surgery & Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Garraway IP; Division of Cancer Biology and Therapeutics, Departments of Surgery & Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Murali R; Department of Urology, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
  • Knudsen BS; Division of Immunology, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Freeman MR; Division of Cancer Biology and Therapeutics, Departments of Surgery & Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Nat Med ; 24(12): 1887-1898, 2018 12.
Article em En | MEDLINE | ID: mdl-30478421
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Adenocarcinoma / Receptores Androgênicos / Proteínas de Homeodomínio / Fator 3-alfa Nuclear de Hepatócito / Neoplasias de Próstata Resistentes à Castração Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Adenocarcinoma / Receptores Androgênicos / Proteínas de Homeodomínio / Fator 3-alfa Nuclear de Hepatócito / Neoplasias de Próstata Resistentes à Castração Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos