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Defective respiration and one-carbon metabolism contribute to impaired naïve T cell activation in aged mice.
Ron-Harel, Noga; Notarangelo, Giulia; Ghergurovich, Jonathan M; Paulo, Joao A; Sage, Peter T; Santos, Daniel; Satterstrom, F Kyle; Gygi, Steven P; Rabinowitz, Joshua D; Sharpe, Arlene H; Haigis, Marcia C.
Afiliação
  • Ron-Harel N; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.
  • Notarangelo G; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.
  • Ghergurovich JM; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544.
  • Paulo JA; Department of Molecular Biology, Princeton University, Princeton, NJ 08544.
  • Sage PT; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.
  • Santos D; Transplantation Research Center, Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
  • Satterstrom FK; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.
  • Gygi SP; Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra 3004-504, Portugal.
  • Rabinowitz JD; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02142.
  • Sharpe AH; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114.
  • Haigis MC; Department of Cell Biology, Harvard Medical School, Boston, MA 02115.
Proc Natl Acad Sci U S A ; 115(52): 13347-13352, 2018 12 26.
Article em En | MEDLINE | ID: mdl-30530686

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ativação Linfocitária / Linfócitos T / Imunidade Inata Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ativação Linfocitária / Linfócitos T / Imunidade Inata Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article