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MDM2-mediated degradation of WRN promotes cellular senescence in a p53-independent manner.
Liu, Boya; Yi, Jingjie; Yang, Xin; Liu, Lu; Lou, Xinlin; Zhang, Zeyuan; Qi, Hao; Wang, Zhe; Zou, Junhua; Zhu, Wei-Guo; Gu, Wei; Luo, Jianyuan.
Afiliação
  • Liu B; Department of Medical Genetics, Peking University Health Science Center, 38 Xueyuan Road, 100191, Beijing, China.
  • Yi J; Institute for Cancer Genetics, Columbia University, New York, NY, 10032, USA.
  • Yang X; Department of Medical Genetics, Peking University Health Science Center, 38 Xueyuan Road, 100191, Beijing, China.
  • Liu L; Department of Medical Genetics, Peking University Health Science Center, 38 Xueyuan Road, 100191, Beijing, China.
  • Lou X; Department of Medical Genetics, Peking University Health Science Center, 38 Xueyuan Road, 100191, Beijing, China.
  • Zhang Z; Department of Medical Genetics, Peking University Health Science Center, 38 Xueyuan Road, 100191, Beijing, China.
  • Qi H; Department of Medical Genetics, Peking University Health Science Center, 38 Xueyuan Road, 100191, Beijing, China.
  • Wang Z; Department of Medical Genetics, Peking University Health Science Center, 38 Xueyuan Road, 100191, Beijing, China.
  • Zou J; Department of Medical Genetics, Peking University Health Science Center, 38 Xueyuan Road, 100191, Beijing, China.
  • Zhu WG; Department of Biochemistry and Molecular Biology, Shenzhen University School of Medicine, Shenzhen, China.
  • Gu W; Institute for Cancer Genetics, Columbia University, New York, NY, 10032, USA.
  • Luo J; Department of Medical Genetics, Peking University Health Science Center, 38 Xueyuan Road, 100191, Beijing, China. luojianyuan@bjmu.edu.cn.
Oncogene ; 38(14): 2501-2515, 2019 04.
Article em En | MEDLINE | ID: mdl-30532073
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Senescência Celular / Proteínas Proto-Oncogênicas c-mdm2 / Helicase da Síndrome de Werner Limite: Humans Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Senescência Celular / Proteínas Proto-Oncogênicas c-mdm2 / Helicase da Síndrome de Werner Limite: Humans Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China