Activation of somatodendritic 5-HT<sub>1A</sub> autoreceptors reduces the acquisition and expression of cued fear in the rat fear-potentiated startle test.

Zhao, Yulong; Bijlsma, Elisabeth Y; Ter Heegde, Freija; Verdouw, Monika P; Garssen, J; Newman-Tancredi, Adrian; Groenink, Lucianne

Activation of somatodendritic 5-HT_1A autoreceptors reduces the acquisition and expression of cued fear in the rat fear-potentiated startle test.

Zhao, Yulong; Bijlsma, Elisabeth Y; Ter Heegde, Freija; Verdouw, Monika P; Garssen, J; Newman-Tancredi, Adrian; Groenink, Lucianne.

Afiliação

Zhao Y; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, Utrecht, The Netherlands.
Bijlsma EY; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, Utrecht, The Netherlands.
Ter Heegde F; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, Utrecht, The Netherlands.
Verdouw MP; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, Utrecht, The Netherlands.
Garssen J; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, Utrecht, The Netherlands.
Newman-Tancredi A; Neurolixis Inc., Dana Point, CA, USA.
Groenink L; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, Utrecht, The Netherlands. l.groenink@uu.nl.

Psychopharmacology (Berl) ; 236(4): 1171-1185, 2019 Apr.

Article em En | MEDLINE | ID: mdl-30539269

Assuntos

Autorreceptores/metabolismo; Sinais (Psicologia); Medo/fisiologia; Medo/psicologia; Receptor 5-HT1A de Serotonina/metabolismo; Reflexo de Sobressalto/fisiologia; 8-Hidroxi-2-(di-n-propilamino)tetralina/farmacologia; Animais; Autorreceptores/agonistas; Dendritos/efeitos dos fármacos; Dendritos/metabolismo; Medo/efeitos dos fármacos; Aprendizagem/efeitos dos fármacos; Aprendizagem/fisiologia; Masculino; Ratos; Ratos Wistar; Reflexo de Sobressalto/efeitos dos fármacos; Serotonina/metabolismo; Agonistas do Receptor 5-HT1 de Serotonina/farmacologia; Antagonistas da Serotonina/farmacologia

Palavras-chave

Anxiety; Biased agonist; Contextual anxiety; Cued fear; Fear conditioning; Fear learning; Fear-potentiated startle; Rats; serotonin1A receptor

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reflexo de Sobressalto / Autorreceptores / Sinais (Psicologia) / Receptor 5-HT1A de Serotonina / Medo Limite: Animals Idioma: En Revista: Psychopharmacology (Berl) Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Holanda

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google