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The orphan nuclear receptor NR4A1 promotes FcεRI-stimulated mast cell activation and anaphylaxis by counteracting the inhibitory LKB1/AMPK axis.
Jin, Fansi; Li, Xian; Deng, Yifeng; Timilshina, Maheshwor; Huang, Bin; Kim, Dong-Young; Chang, Jae-Hoon; Ichinose, Hiroshi; Baek, Suk-Hwan; Murakami, Makoto; Lee, Youn Ju; Chang, Hyeun Wook.
Afiliação
  • Jin F; College of Pharmacy, Yeungnam University, Gyeongsan, Korea.
  • Li X; College of Pharmacy, Yeungnam University, Gyeongsan, Korea.
  • Deng Y; College of Pharmacy, Yeungnam University, Gyeongsan, Korea.
  • Timilshina M; College of Pharmacy, Yeungnam University, Gyeongsan, Korea.
  • Huang B; Department of Biochemistry and Molecular Biology, College of Medicine, Yeungnam University, Daegu, Korea.
  • Kim DY; College of Pharmacy, Yeungnam University, Gyeongsan, Korea.
  • Chang JH; College of Pharmacy, Yeungnam University, Gyeongsan, Korea.
  • Ichinose H; School of Life Science and Technology, Tokyo Institute of Technology, Yokohama, Japan.
  • Baek SH; Department of Biochemistry and Molecular Biology, College of Medicine, Yeungnam University, Daegu, Korea.
  • Murakami M; Laboratory of Microenvironmental Metabolic Health Sciences, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Hongo, Bunkyo-ku, Japan.
  • Lee YJ; Department of Pharmacology, School of Medicine, Catholic University of Daegu, Daegu, Korea.
  • Chang HW; College of Pharmacy, Yeungnam University, Gyeongsan, Korea.
Allergy ; 74(6): 1145-1156, 2019 06.
Article em En | MEDLINE | ID: mdl-30565708
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de IgE / Proteínas Serina-Treonina Quinases / Proteínas Quinases Ativadas por AMP / Membro 1 do Grupo A da Subfamília 4 de Receptores Nucleares / Anafilaxia / Mastócitos Limite: Animals / Humans / Male Idioma: En Revista: Allergy Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de IgE / Proteínas Serina-Treonina Quinases / Proteínas Quinases Ativadas por AMP / Membro 1 do Grupo A da Subfamília 4 de Receptores Nucleares / Anafilaxia / Mastócitos Limite: Animals / Humans / Male Idioma: En Revista: Allergy Ano de publicação: 2019 Tipo de documento: Article