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A chemical biology toolbox to study protein methyltransferases and epigenetic signaling.
Scheer, Sebastian; Ackloo, Suzanne; Medina, Tiago S; Schapira, Matthieu; Li, Fengling; Ward, Jennifer A; Lewis, Andrew M; Northrop, Jeffrey P; Richardson, Paul L; Kaniskan, H Ümit; Shen, Yudao; Liu, Jing; Smil, David; McLeod, David; Zepeda-Velazquez, Carlos A; Luo, Minkui; Jin, Jian; Barsyte-Lovejoy, Dalia; Huber, Kilian V M; De Carvalho, Daniel D; Vedadi, Masoud; Zaph, Colby; Brown, Peter J; Arrowsmith, Cheryl H.
Afiliação
  • Scheer S; Infection and Immunity Program, Monash Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, 3800, Australia.
  • Ackloo S; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada.
  • Medina TS; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 2M9, Canada.
  • Schapira M; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada.
  • Li F; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, M5S 1A8, Canada.
  • Ward JA; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada.
  • Lewis AM; Structural Genomics Consortium, University of Oxford, Oxford, OX3 7DQ, UK.
  • Northrop JP; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, UK.
  • Richardson PL; Structural Genomics Consortium, University of Oxford, Oxford, OX3 7DQ, UK.
  • Kaniskan HÜ; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, UK.
  • Shen Y; Infection and Immunity Program, Monash Biomedicine Discovery Institute, Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, 3800, Australia.
  • Liu J; AbbVie Inc., 1 North Waukegan Rd, North Chicago, IL, 60064, USA.
  • Smil D; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • McLeod D; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Zepeda-Velazquez CA; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Luo M; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada.
  • Jin J; Ontario Institute for Cancer Research, Toronto, ON, M5G 0A3, Canada.
  • Barsyte-Lovejoy D; Ontario Institute for Cancer Research, Toronto, ON, M5G 0A3, Canada.
  • Huber KVM; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • De Carvalho DD; Program of Pharmacology, Weill Cornell Medical College of Cornell University, New York, NY, 10021, USA.
  • Vedadi M; Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences and Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Zaph C; Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada.
  • Brown PJ; Structural Genomics Consortium, University of Oxford, Oxford, OX3 7DQ, UK.
  • Arrowsmith CH; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, UK.
Nat Commun ; 10(1): 19, 2019 01 03.
Article em En | MEDLINE | ID: mdl-30604761
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Metiltransferases / Histonas / Processamento de Proteína Pós-Traducional / Epigênese Genética / Inibidores Enzimáticos Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Austrália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Metiltransferases / Histonas / Processamento de Proteína Pós-Traducional / Epigênese Genética / Inibidores Enzimáticos Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Austrália