Synthesis of Pyridopyrazine-1,6-dione Î³-Secretase Modulators via Selective 4-Methylimidazole N<sup>1</sup>-Buchwald Arylation.

Xie, Longfei; Am Ende, Christopher W; Pettersson, Martin; Rankic, Danica A; Sach, Neal W; Sakya, Subbas; Humphrey, John M

Synthesis of Pyridopyrazine-1,6-dione Î³-Secretase Modulators via Selective 4-Methylimidazole N¹-Buchwald Arylation.

Xie, Longfei; Am Ende, Christopher W; Pettersson, Martin; Rankic, Danica A; Sach, Neal W; Sakya, Subbas; Humphrey, John M.

Afiliação

Xie L; Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
Am Ende CW; Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
Pettersson M; Pfizer Worldwide Research and Development , 1 Portland Street , Cambridge , Massachusetts 02139 , United States.
Rankic DA; Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
Sach NW; Pfizer Worldwide Research and Development , 10770 Science Center Drive , San Diego , California 92121 , United States.
Sakya S; Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
Humphrey JM; Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.

J Org Chem ; 84(8): 4921-4925, 2019 04 19.

Article em En | MEDLINE | ID: mdl-30620601

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Org Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

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