Systemic AAV vectors for widespread and targeted gene delivery in rodents.

Challis, Rosemary C; Ravindra Kumar, Sripriya; Chan, Ken Y; Challis, Collin; Beadle, Keith; Jang, Min J; Kim, Hyun Min; Rajendran, Pradeep S; Tompkins, John D; Shivkumar, Kalyanam; Deverman, Benjamin E; Gradinaru, Viviana

Challis, Rosemary C; Ravindra Kumar, Sripriya; Chan, Ken Y; Challis, Collin; Beadle, Keith; Jang, Min J; Kim, Hyun Min; Rajendran, Pradeep S; Tompkins, John D; Shivkumar, Kalyanam; Deverman, Benjamin E; Gradinaru, Viviana.

Afiliação

Challis RC; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Ravindra Kumar S; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Chan KY; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Challis C; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Beadle K; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Jang MJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Kim HM; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Rajendran PS; Cardiac Arrhythmia Center and Neurocardiology Research Center of Excellence, University of California, Los Angeles, Los Angeles, CA, USA.
Tompkins JD; Cardiac Arrhythmia Center and Neurocardiology Research Center of Excellence, University of California, Los Angeles, Los Angeles, CA, USA.
Shivkumar K; Cardiac Arrhythmia Center and Neurocardiology Research Center of Excellence, University of California, Los Angeles, Los Angeles, CA, USA.
Deverman BE; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Gradinaru V; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA. viviana@caltech.edu.

Nat Protoc ; 14(2): 379-414, 2019 02.

Article em En | MEDLINE | ID: mdl-30626963

Assuntos

Dependovirus/genética; Técnicas de Transferência de Genes; Terapia Genética/métodos; Vetores Genéticos/química; Animais; Encéfalo/citologia; Encéfalo/metabolismo; Capsídeo/química; Capsídeo/metabolismo; Dependovirus/metabolismo; Trato Gastrointestinal/citologia; Trato Gastrointestinal/metabolismo; Genes Reporter; Vetores Genéticos/metabolismo; Proteínas de Fluorescência Verde/genética; Proteínas de Fluorescência Verde/metabolismo; Células HEK293; Humanos; Injeções Intravenosas; Proteínas Luminescentes/genética; Proteínas Luminescentes/metabolismo; Camundongos; Miocárdio/citologia; Miocárdio/metabolismo; Ratos; Ratos Long-Evans; Ratos Sprague-Dawley; Medula Espinal/citologia; Medula Espinal/metabolismo; Transgenes; Proteína Vermelha Fluorescente

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia Genética / Técnicas de Transferência de Genes / Dependovirus / Vetores Genéticos Limite: Animals / Humans Idioma: En Revista: Nat Protoc Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

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