Production and distribution of chromosome aberrations in human lymphocytes by particle beams with different LET.
Radiat Environ Biophys
; 58(1): 99-108, 2019 03.
Article
em En
| MEDLINE
| ID: mdl-30656467
ABSTRACT
We investigated induction of chromosome aberrations (CA) in human lymphocytes when exposed to 150 MeV and spread out Bragg peak (SOBP) proton beams, and 199 MeV/u carbon beam which are currently widely used for cancer treatment and simultaneously are important components of cosmic radiation. For a comparison, the boron ions of much lower energy 22 MeV/u and a 60Co γ rays were used. Dose-effect curves as well as the distributions of CA were studied using Poisson and Neyman type A statistics. Systematics of experimentally determined parameters, their dependence on applied doses and irradiation quality are presented.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Linfócitos
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Aberrações Cromossômicas
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Cromossomos Humanos
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Transferência Linear de Energia
Limite:
Humans
Idioma:
En
Revista:
Radiat Environ Biophys
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Polônia