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Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease.
Guha, Sujay; Konkwo, Chigoziri; Lavorato, Manuela; Mathew, Neal D; Peng, Min; Ostrovsky, Julian; Kwon, Young-Joon; Polyak, Erzsebet; Lightfoot, Richard; Seiler, Christoph; Xiao, Rui; Bennett, Michael; Zhang, Zhe; Nakamaru-Ogiso, Eiko; Falk, Marni J.
Afiliação
  • Guha S; Mitochondrial Medicine Frontier Program, Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Konkwo C; Mitochondrial Medicine Frontier Program, Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Lavorato M; Mitochondrial Medicine Frontier Program, Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Mathew ND; Mitochondrial Medicine Frontier Program, Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Peng M; Mitochondrial Medicine Frontier Program, Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Ostrovsky J; Mitochondrial Medicine Frontier Program, Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Kwon YJ; Mitochondrial Medicine Frontier Program, Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Polyak E; Mitochondrial Medicine Frontier Program, Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Lightfoot R; Mitochondrial Medicine Frontier Program, Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Seiler C; Aquatics Core Facility, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Xiao R; Department of Statistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Bennett M; Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Zhang Z; Center for Biomedical Informatics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Nakamaru-Ogiso E; Mitochondrial Medicine Frontier Program, Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Falk MJ; Mitochondrial Medicine Frontier Program, Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Hum Mol Genet ; 28(11): 1837-1852, 2019 06 01.
Article em En | MEDLINE | ID: mdl-30668749
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cisteamina / Doenças Mitocondriais / Proteínas de Caenorhabditis elegans / NADH Desidrogenase / Antioxidantes Limite: Animals / Humans Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cisteamina / Doenças Mitocondriais / Proteínas de Caenorhabditis elegans / NADH Desidrogenase / Antioxidantes Limite: Animals / Humans Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos