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Improved TMC1 gene therapy restores hearing and balance in mice with genetic inner ear disorders.
Nist-Lund, Carl A; Pan, Bifeng; Patterson, Amy; Asai, Yukako; Chen, Tianwen; Zhou, Wu; Zhu, Hong; Romero, Sandra; Resnik, Jennifer; Polley, Daniel B; Géléoc, Gwenaelle S; Holt, Jeffrey R.
Afiliação
  • Nist-Lund CA; Department of Otolaryngology and F.M. Kirby Neurobiology Center, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA.
  • Pan B; Department of Otolaryngology and F.M. Kirby Neurobiology Center, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA.
  • Patterson A; Department of Otolaryngology, Harvard Medical School, Boston, MA, 02139, USA.
  • Asai Y; Department of Otolaryngology and F.M. Kirby Neurobiology Center, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA.
  • Chen T; Department of Otolaryngology and F.M. Kirby Neurobiology Center, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA.
  • Zhou W; Department of Otolaryngology, Harvard Medical School, Boston, MA, 02139, USA.
  • Zhu H; Department of Otolaryngology and Communicative Sciences, University of Mississippi Medical Center, Jackson, MS, 39216, USA.
  • Romero S; Department of Otolaryngology and Communicative Sciences, University of Mississippi Medical Center, Jackson, MS, 39216, USA.
  • Resnik J; Department of Otolaryngology and Communicative Sciences, University of Mississippi Medical Center, Jackson, MS, 39216, USA.
  • Polley DB; Eaton-Peabody Laboratories, Massachusetts Eye and Ear Infirmary, Boston, MA, 02139, USA.
  • Géléoc GS; Department of Otolaryngology, Harvard Medical School, Boston, MA, 02139, USA.
  • Holt JR; Eaton-Peabody Laboratories, Massachusetts Eye and Ear Infirmary, Boston, MA, 02139, USA.
Nat Commun ; 10(1): 236, 2019 01 22.
Article em En | MEDLINE | ID: mdl-30670701

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia Genética / Predisposição Genética para Doença / Surdez / Perda Auditiva / Doenças do Labirinto / Proteínas de Membrana Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia Genética / Predisposição Genética para Doença / Surdez / Perda Auditiva / Doenças do Labirinto / Proteínas de Membrana Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos