Synthesis and Investigation of Phthalazinones as Antitubercular Agents.

Santoso, Kristiana T; Cheung, Chen-Yi; Hards, Kiel; Cook, Gregory M; Stocker, Bridget L; Timmer, Mattie S M

Santoso, Kristiana T; Cheung, Chen-Yi; Hards, Kiel; Cook, Gregory M; Stocker, Bridget L; Timmer, Mattie S M.

Afiliação

Santoso KT; School of Chemical and Physical Sciences, Victoria University of Wellington, P.O. Box 600, 6140, Wellington, New Zealand.
Cheung CY; Centre for Biodiscovery, Victoria University of Wellington, P.O. Box 600, 6140, Wellington, New Zealand.
Hards K; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand.
Cook GM; Department of Microbiology and Immunology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Stocker BL; Department of Microbiology and Immunology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
Timmer MSM; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand.

Chem Asian J ; 14(8): 1278-1285, 2019 Apr 15.

Article em En | MEDLINE | ID: mdl-30680937

Assuntos

Antituberculosos/síntese química; Antituberculosos/farmacologia; Mycobacterium tuberculosis/efeitos dos fármacos; Ftalazinas/síntese química; Ftalazinas/farmacologia; Antituberculosos/química; Relação Dose-Resposta a Droga; Testes de Sensibilidade Microbiana; Modelos Moleculares; Estrutura Molecular; Ftalazinas/química; Relação Estrutura-Atividade

Palavras-chave

Medicinal Chemistry; Nitrogen Heterocycles; Phthalazinones; Tuberculosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ftalazinas / Mycobacterium tuberculosis / Antituberculosos Idioma: En Revista: Chem Asian J Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Nova Zelândia

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