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A pair of peptides inhibits seeding of the hormone transporter transthyretin into amyloid fibrils.
Saelices, Lorena; Nguyen, Binh A; Chung, Kevin; Wang, Yifei; Ortega, Alfredo; Lee, Ji H; Coelho, Teresa; Bijzet, Johan; Benson, Merrill D; Eisenberg, David S.
Afiliação
  • Saelices L; From the Departments of Biological Chemistry and Chemistry and Biochemistry, Howard Hughes Medical Institute, UCLA-DOE Institute, Molecular Biology Institute, UCLA, Los Angeles, California 90095-1570.
  • Nguyen BA; From the Departments of Biological Chemistry and Chemistry and Biochemistry, Howard Hughes Medical Institute, UCLA-DOE Institute, Molecular Biology Institute, UCLA, Los Angeles, California 90095-1570.
  • Chung K; From the Departments of Biological Chemistry and Chemistry and Biochemistry, Howard Hughes Medical Institute, UCLA-DOE Institute, Molecular Biology Institute, UCLA, Los Angeles, California 90095-1570.
  • Wang Y; From the Departments of Biological Chemistry and Chemistry and Biochemistry, Howard Hughes Medical Institute, UCLA-DOE Institute, Molecular Biology Institute, UCLA, Los Angeles, California 90095-1570.
  • Ortega A; From the Departments of Biological Chemistry and Chemistry and Biochemistry, Howard Hughes Medical Institute, UCLA-DOE Institute, Molecular Biology Institute, UCLA, Los Angeles, California 90095-1570.
  • Lee JH; From the Departments of Biological Chemistry and Chemistry and Biochemistry, Howard Hughes Medical Institute, UCLA-DOE Institute, Molecular Biology Institute, UCLA, Los Angeles, California 90095-1570.
  • Coelho T; the Neurophysiology Department and Corino de Andrade Unit, Hospital Santo António, Centro Hospitalar do Porto, Porto 4099-001, Portugal.
  • Bijzet J; the Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, 9713 GZ, The Netherlands.
  • Benson MD; the Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202.
  • Eisenberg DS; From the Departments of Biological Chemistry and Chemistry and Biochemistry, Howard Hughes Medical Institute, UCLA-DOE Institute, Molecular Biology Institute, UCLA, Los Angeles, California 90095-1570. Electronic address: david@mbi.ucla.edu.
J Biol Chem ; 294(15): 6130-6141, 2019 04 12.
Article em En | MEDLINE | ID: mdl-30733338
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Pré-Albumina / Neuropatias Amiloides Familiares / Agregados Proteicos / Amiloide Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Biol Chem Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Pré-Albumina / Neuropatias Amiloides Familiares / Agregados Proteicos / Amiloide Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Biol Chem Ano de publicação: 2019 Tipo de documento: Article