Challenges for mesenchymal stromal cell therapies.

Martin, Ivan; Galipeau, Jacques; Kessler, Charles; Le Blanc, Katarina; Dazzi, Francesco

Martin, Ivan; Galipeau, Jacques; Kessler, Charles; Le Blanc, Katarina; Dazzi, Francesco.

Afiliação

Martin I; Department of Biomedicine, University Hospital Basel, University of Basel, 4031 Basel, Switzerland. ivan.martin@usb.ch.
Galipeau J; Department of Medicine, University of Wisconsin Carbone Comprehensive Cancer Center, Madison, WI 53715, USA.
Kessler C; Health Directorate, Directorate General for Research and Innovation, European Commission, 1049 Brussels, Belgium.
Le Blanc K; Center for Hematology and Regenerative Medicine, Karolinska University Hospital, 171 77 Stockholm, Sweden.
Dazzi F; School of Cancer and Pharmacological Sciences, King's Health Partners Cancer Research UK Centre, King's College London, London SE1 9NH, UK.

Sci Transl Med ; 11(480)2019 02 20.

Article em En | MEDLINE | ID: mdl-30787168

ABSTRACT

ABSTRACT

Clinical trials of mesenchymal stromal cell therapies reveal a challenging heterogeneous landscape, including diverse therapeutic targets, patient categories, cell sources, and potential mechanisms of action.

Assuntos

Transplante de Células-Tronco Mesenquimais; Células-Tronco Mesenquimais/citologia; Animais; Ensaios Clínicos como Assunto; Humanos; Imunomodulação

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Células-Tronco Mesenquimais / Células-Tronco Mesenquimais Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Suíça

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