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Pharmacological inhibition of the IKKε/TBK-1 axis potentiates the anti-tumour and anti-metastatic effects of Docetaxel in mouse models of breast cancer.
Bishop, Ryan T; Marino, Silvia; de Ridder, Daniëlle; Allen, Richard J; Lefley, Diane V; Sims, Andrew H; Wang, Ning; Ottewell, Penelope D; Idris, Aymen I.
Afiliação
  • Bishop RT; Department of Oncology and Metabolism, Medical School, Beech Hill Road, Sheffield, S10 2RX, UK.
  • Marino S; Department of Oncology and Metabolism, Medical School, Beech Hill Road, Sheffield, S10 2RX, UK; Bone and Cancer Group, Edinburgh Cancer Research Centre, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XR, UK.
  • de Ridder D; Department of Oncology and Metabolism, Medical School, Beech Hill Road, Sheffield, S10 2RX, UK.
  • Allen RJ; Department of Oncology and Metabolism, Medical School, Beech Hill Road, Sheffield, S10 2RX, UK.
  • Lefley DV; Department of Oncology and Metabolism, Medical School, Beech Hill Road, Sheffield, S10 2RX, UK.
  • Sims AH; Applied Bioinformatics of Cancer, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.
  • Wang N; Department of Oncology and Metabolism, Medical School, Beech Hill Road, Sheffield, S10 2RX, UK.
  • Ottewell PD; Department of Oncology and Metabolism, Medical School, Beech Hill Road, Sheffield, S10 2RX, UK.
  • Idris AI; Department of Oncology and Metabolism, Medical School, Beech Hill Road, Sheffield, S10 2RX, UK; Bone and Cancer Group, Edinburgh Cancer Research Centre, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XR, UK. Electronic address: aymen.idris@sheffield.ac.uk.
Cancer Lett ; 450: 76-87, 2019 05 28.
Article em En | MEDLINE | ID: mdl-30790681
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Proteínas Serina-Treonina Quinases / Quinase I-kappa B / Docetaxel / Aminopiridinas / Neoplasias Mamárias Experimentais Limite: Animals / Female / Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Proteínas Serina-Treonina Quinases / Quinase I-kappa B / Docetaxel / Aminopiridinas / Neoplasias Mamárias Experimentais Limite: Animals / Female / Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido