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Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates.
Costa, Maria José; Kudaravalli, Jyothirmayee; Ma, Jing-Tyan; Ho, Wei-Hsien; Delaria, Kathy; Holz, Charles; Stauffer, Angela; Chunyk, Allison Given; Zong, Qing; Blasi, Eileen; Buetow, Bernard; Tran, Thomas-Toan; Lindquist, Kevin; Dorywalska, Magdalena; Rajpal, Arvind; Shelton, David L; Strop, Pavel; Liu, Shu-Hui.
Afiliação
  • Costa MJ; Cancer Immunology Discovery, Oncology Research and Development, Worldwide Research and Development, Pfizer Inc., 230 E Grand Ave, South San Francisco, CA, 94080, USA. mariajstcosta@gmail.com.
  • Kudaravalli J; Cancer Immunology Discovery, Oncology Research and Development, Worldwide Research and Development, Pfizer Inc., 230 E Grand Ave, South San Francisco, CA, 94080, USA.
  • Ma JT; Cancer Immunology Discovery, Oncology Research and Development, Worldwide Research and Development, Pfizer Inc., 230 E Grand Ave, South San Francisco, CA, 94080, USA.
  • Ho WH; Cancer Immunology Discovery, Oncology Research and Development, Worldwide Research and Development, Pfizer Inc., 230 E Grand Ave, South San Francisco, CA, 94080, USA.
  • Delaria K; Alector, 151, Oyster Point Blvd, suite 300, South San Francisco, CA, 94080, USA.
  • Holz C; Cancer Immunology Discovery, Oncology Research and Development, Worldwide Research and Development, Pfizer Inc., 230 E Grand Ave, South San Francisco, CA, 94080, USA.
  • Stauffer A; Grifols Diagnostic Solutions, 6455 Christie Ave B-334C, Emeryville, CA, 94608, USA.
  • Chunyk AG; Cancer Immunology Discovery, Oncology Research and Development, Worldwide Research and Development, Pfizer Inc., 230 E Grand Ave, South San Francisco, CA, 94080, USA.
  • Zong Q; Grifols Diagnostic Solutions, 6455 Christie Ave B-334C, Emeryville, CA, 94608, USA.
  • Blasi E; BioMedicine Design, Medicinal Sciences, Worldwide Research and Development, Pfizer Inc., 10646 Science Center Dr, San Diego, CA, 92121, USA.
  • Buetow B; BioMedicine Design, Medicinal Sciences, Worldwide Research and Development, Pfizer Inc., 10646 Science Center Dr, San Diego, CA, 92121, USA.
  • Tran TT; Drug Safety Research and Development, Worldwide Research and Development, Pfizer Inc., 10646 Science Center Dr, San Diego, CA, 92121, USA.
  • Lindquist K; Drug Safety Research and Development, Worldwide Research and Development, Pfizer Inc., 10646 Science Center Dr, San Diego, CA, 92121, USA.
  • Dorywalska M; Drug Safety Research and Development, Worldwide Research and Development, Pfizer Inc., 10646 Science Center Dr, San Diego, CA, 92121, USA.
  • Rajpal A; Cancer Immunology Discovery, Oncology Research and Development, Worldwide Research and Development, Pfizer Inc., 230 E Grand Ave, South San Francisco, CA, 94080, USA.
  • Shelton DL; NGM Biopharmaceuticals, Inc, 630 Gateway Blvd, South San Francisco, CA, 94080, USA.
  • Strop P; Cancer Immunology Discovery, Oncology Research and Development, Worldwide Research and Development, Pfizer Inc., 230 E Grand Ave, South San Francisco, CA, 94080, USA.
  • Liu SH; Cancer Immunology Discovery, Oncology Research and Development, Worldwide Research and Development, Pfizer Inc., 230 E Grand Ave, South San Francisco, CA, 94080, USA.
Sci Rep ; 9(1): 2443, 2019 02 21.
Article em En | MEDLINE | ID: mdl-30792442
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Imunoconjugados / Receptores CXCR4 / Antineoplásicos Imunológicos Tipo de estudo: Prognostic_studies Idioma: En Revista: Sci Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Imunoconjugados / Receptores CXCR4 / Antineoplásicos Imunológicos Tipo de estudo: Prognostic_studies Idioma: En Revista: Sci Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos