Protective Effects of Serotonin and its Derivatives, N-Feruloylserotonin and N-(p-Coumaroyl) Serotonin, Against Cisplatin-Induced Renal Damage in Mice.

Park, Chan Hum; Lee, Ah Young; Kim, Ji Hyun; Seong, Su Hui; Cho, Eun Ju; Choi, Jae Sue; Kim, Min Jo; Yang, Siyoung; Yokozawa, Takako; Shin, Yu Su

Park, Chan Hum; Lee, Ah Young; Kim, Ji Hyun; Seong, Su Hui; Cho, Eun Ju; Choi, Jae Sue; Kim, Min Jo; Yang, Siyoung; Yokozawa, Takako; Shin, Yu Su.

Afiliação

Park CH; * Department of Medicinal Crop Research, National Institute of Horticultural and Herbal Science, Rural Development Administration, Eumseong 369-873, Republic of Korea.
Lee AY; Department of Food Science and Nutrition, Pusan National University, Busan 46241, Republic of Korea.
Kim JH; Department of Food Science and Nutrition, Pusan National University, Busan 46241, Republic of Korea.
Seong SH; Department of Food and Life Science, Pukyong National University, Busan 608-737, Republic of Korea.
Cho EJ; Department of Food Science and Nutrition, Pusan National University, Busan 46241, Republic of Korea.
Choi JS; Department of Food and Life Science, Pukyong National University, Busan 608-737, Republic of Korea.
Kim MJ; * Department of Medicinal Crop Research, National Institute of Horticultural and Herbal Science, Rural Development Administration, Eumseong 369-873, Republic of Korea.
Yang S; § Department of Pharmacology, Ajou University School of Medicine, Suwon 16499, Republic of Korea.
Yokozawa T; ¶ Graduate School of Science and Engineering for Research, University of Toyama, Toyama 930-8555, Japan.
Shin YS; * Department of Medicinal Crop Research, National Institute of Horticultural and Herbal Science, Rural Development Administration, Eumseong 369-873, Republic of Korea.

Am J Chin Med ; 47(2): 369-383, 2019.

Article em En | MEDLINE | ID: mdl-30827154

Assuntos

Injúria Renal Aguda/induzido quimicamente; Injúria Renal Aguda/prevenção & controle; Antineoplásicos/efeitos adversos; Cisplatino/efeitos adversos; Fitoterapia; Serotonina/análogos & derivados; Animais; Apoptose/efeitos dos fármacos; Apoptose/genética; Nitrogênio da Ureia Sanguínea; Carthamus tinctorius/química; Creatinina/sangue; Modelos Animais de Doenças; Expressão Gênica; Glutationa Peroxidase/genética; Glutationa Peroxidase/metabolismo; Inflamação/genética; Injeções Intraperitoneais; Rim/metabolismo; Camundongos; Camundongos Endogâmicos BALB C; Proteínas Quinases Ativadas por Mitógeno/genética; Proteínas Quinases Ativadas por Mitógeno/metabolismo; Estresse Oxidativo/efeitos dos fármacos; Estresse Oxidativo/genética; Serotonina/administração & dosagem; Serotonina/farmacologia

Palavras-chave

Cisplatin; <ns0:math><mi>N</mi></math>-(<ns0:math><mi>p</mi></math>-Coumaroyl) Serotonin; <ns0:math><mi>N</mi></math>-Feruloylserotonin; Nephrotoxicity; Safflower Seed; Serotonin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Serotonina / Cisplatino / Injúria Renal Aguda / Fitoterapia / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Am J Chin Med Ano de publicação: 2019 Tipo de documento: Article

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