Serum Testosterone 60 Months after Passive-Scatter Proton Therapy for Localized Prostate Cancer.
Cancer Invest
; 37(2): 85-89, 2019.
Article
em En
| MEDLINE
| ID: mdl-30836776
ABSTRACT
Studies demonstrate a decline of â¼10% in serum testosterone (ST) level after X-ray radiotherapy for prostate cancer. We evaluated changes in ST for patients with low- and intermediate-risk prostate cancer receiving 70-82Gy(RBE) using passive-scatter proton therapy (PT). ST was checked at baseline (n = 358) and at 60+ months after PT (n = 166). The median baseline ST was 363.3 ng/dl (range, 82.0-974.0). The median ST 5 years after PT was 391.5 ng/dl (range, 108.0-1061.0). The difference was not statistically significant (p = 0.9341). Passive-scatter PT was not associated with testosterone suppression at 5 years, suggesting that protons may cause less out-of-field scatter radiation than X-rays.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
/
Testosterona
Limite:
Humans
/
Male
Idioma:
En
Revista:
Cancer Invest
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Estados Unidos