Eosinophilic esophagitis after total gastrectomy treated with proton pump inhibitors: a case report.
Clin J Gastroenterol
; 12(5): 420-423, 2019 Oct.
Article
em En
| MEDLINE
| ID: mdl-30848447
ABSTRACT
Eosinophilic esophagitis (EoE) is a chronic, immune-mediated disorder in the esophagus characterized by symptoms related to esophageal dysfunction and eosinophil-predominant inflammation. EoE and Gastro Esophageal Reflux Disease (GERD) are known not to be mutually exclusive and share a complex relationship. Proton pump inhibitors (PPIs), which are generally used in the treatment of GERD, could be used to treat esophageal eosinophilia in suspected EoE. We report a rare case of EoE after total gastrectomy that responded to PPIs. Our case indicates that the onset of EoE does not necessarily require an acid reflux-induced antigen-mediated drive, and the action of PPIs in patients with active EoE is unrelated to gastric acid suppression.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Inibidores da Bomba de Prótons
/
Esofagite Eosinofílica
/
Gastrectomia
Tipo de estudo:
Etiology_studies
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Clin J Gastroenterol
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Japão