Molecular evolutionary and structural analysis of familial exudative vitreoretinopathy associated FZD4 gene.

Seemab, Suman; Pervaiz, Nashaiman; Zehra, Rabail; Anwar, Saneela; Bao, Yiming; Abbasi, Amir Ali

Seemab, Suman; Pervaiz, Nashaiman; Zehra, Rabail; Anwar, Saneela; Bao, Yiming; Abbasi, Amir Ali.

Afiliação

Seemab S; National Center for Bioinformatics, Program of Comparative and Evolutionary Genomics, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
Pervaiz N; National Center for Bioinformatics, Program of Comparative and Evolutionary Genomics, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
Zehra R; National Center for Bioinformatics, Program of Comparative and Evolutionary Genomics, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
Anwar S; National Center for Bioinformatics, Program of Comparative and Evolutionary Genomics, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan.
Bao Y; BIG Data Center & CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China. baoym@big.ac.cn.
Abbasi AA; National Center for Bioinformatics, Program of Comparative and Evolutionary Genomics, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan. abbasiam@qau.edu.pk.

BMC Evol Biol ; 19(1): 72, 2019 03 08.

Article em En | MEDLINE | ID: mdl-30849938

Assuntos

Evolução Molecular; Oftalmopatias Hereditárias/genética; Receptores Frizzled/química; Receptores Frizzled/genética; Doenças Retinianas/genética; Vitreorretinopatias Exsudativas Familiares; Humanos; Proteínas Mutantes/química; Proteínas Mutantes/genética; Mutação de Sentido Incorreto/genética; Filogenia; Domínios Proteicos

Palavras-chave

FZD4; Familial exudative vitreoretinopathy; Frizzled; G-protein coupled receptors; Metazoans; Multigene family; Phylogenetic analysis; Structural analysis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Retinianas / Oftalmopatias Hereditárias / Evolução Molecular / Receptores Frizzled Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: BMC Evol Biol Assunto da revista: BIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Paquistão

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