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Clinical characteristics and glucose-lowering drug utilization among patients initiating liraglutide in Denmark: a routine clinical care prescription study.
Knudsen, Jakob S; Thomsen, Reimar W; Pottegård, Anton; Knop, Filip K; Sørensen, Henrik T.
Afiliação
  • Knudsen JS; Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
  • Thomsen RW; Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
  • Pottegård A; Department of Clinical Pharmacology and Pharmacy, Clinical Pharmacology and Pharmacy, University of Southern Denmark, Odense, Denmark.
  • Knop FK; Deparment of Clinical Metabolic Physiology, Clinical Metabolic Physiology, Steno Diabetes Center Copenhagen, Gentofte Hospital, Hellerup, Denmark.
  • Sørensen HT; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
J Diabetes ; 11(8): 690-694, 2019 Aug.
Article em En | MEDLINE | ID: mdl-30893522
ABSTRACT
Highlights This population-based real-world prescription study characterized all new users of liraglutide in northern Denmark from 2009 to 2015. More than half (57%) the patients had liraglutide prescribed as part of drug combinations outside the originally approved indications. Comorbidities or diabetes complications were present in most patients, with the highest prevalence observed among the 73% of initiators who would have been ineligible for the Liraglutide Effect and Action in Diabetes (LEAD) 1-5 trials that led to liraglutide registration, underscoring the need for further post-marketing studies.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Padrões de Prática Médica / Diabetes Mellitus Tipo 2 / Uso de Medicamentos / Liraglutida / Glucose / Hipoglicemiantes Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: J Diabetes Assunto da revista: ENDOCRINOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Dinamarca

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Padrões de Prática Médica / Diabetes Mellitus Tipo 2 / Uso de Medicamentos / Liraglutida / Glucose / Hipoglicemiantes Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: J Diabetes Assunto da revista: ENDOCRINOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Dinamarca