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S27 of IFNα1 Contributes to Its Low Affinity for IFNAR2 and Weak Antiviral Activity.
Sharma, Nikunj; O'Neal, Anya J; Gonzalez, Christian; Wittling, Megen; Gjinaj, Erisa; Parsons, Lisa M; Panda, Debasis; Khalenkov, Alexey; Scott, Dorothy; Misra, Saurav; Rabin, Ronald L.
Afiliação
  • Sharma N; 1 Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland.
  • O'Neal AJ; 1 Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland.
  • Gonzalez C; 1 Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland.
  • Wittling M; 1 Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland.
  • Gjinaj E; 1 Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland.
  • Parsons LM; 1 Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland.
  • Panda D; 1 Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland.
  • Khalenkov A; 2 Office of Tissues and Advanced Therapies, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland.
  • Scott D; 2 Office of Tissues and Advanced Therapies, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland.
  • Misra S; 3 Department of Biochemistry and Molecular Biophysics, Kansas State University, Manhattan, Kansas.
  • Rabin RL; 1 Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland.
J Interferon Cytokine Res ; 39(5): 283-292, 2019 05.
Article em En | MEDLINE | ID: mdl-30920934
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Serina / Interferon-alfa / Vesiculovirus / Receptor de Interferon alfa e beta Limite: Humans Idioma: En Revista: J Interferon Cytokine Res Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Serina / Interferon-alfa / Vesiculovirus / Receptor de Interferon alfa e beta Limite: Humans Idioma: En Revista: J Interferon Cytokine Res Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2019 Tipo de documento: Article