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Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer.
Petros, Andrew M; Korepanova, Alla; Jakob, Clarissa G; Qiu, Wei; Panchal, Sanjay C; Wang, Jie; Dietrich, Justin D; Brewer, Jason T; Pohlki, Frauke; Kling, Andreas; Wilcox, Kyle; Lakics, Viktor; Bahnassawy, Lamiaa; Reinhardt, Peter; Partha, Sarathy Karunan; Bodelle, Pierre M; Lake, Marc; Charych, Erik I; Stoll, Vincent S; Sun, Chaohong; Mohler, Eric G.
Afiliação
  • Petros AM; Research & Development , AbbVie , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Korepanova A; Research & Development , AbbVie , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Jakob CG; Research & Development , AbbVie , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Qiu W; Research & Development , AbbVie , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Panchal SC; Research & Development , AbbVie , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Wang J; Research & Development , AbbVie , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Dietrich JD; Research & Development , AbbVie , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Brewer JT; Research & Development , AbbVie , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Pohlki F; Neuroscience Research , AbbVie Deutschland GmbH & Co. KG , Knollstrasse , 67061 Ludwigshafen , Germany.
  • Kling A; Neuroscience Research , AbbVie Deutschland GmbH & Co. KG , Knollstrasse , 67061 Ludwigshafen , Germany.
  • Wilcox K; Research & Development , AbbVie , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Lakics V; Neuroscience Research , AbbVie Deutschland GmbH & Co. KG , Knollstrasse , 67061 Ludwigshafen , Germany.
  • Bahnassawy L; Neuroscience Research , AbbVie Deutschland GmbH & Co. KG , Knollstrasse , 67061 Ludwigshafen , Germany.
  • Reinhardt P; Neuroscience Research , AbbVie Deutschland GmbH & Co. KG , Knollstrasse , 67061 Ludwigshafen , Germany.
  • Partha SK; Research & Development , AbbVie , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Bodelle PM; Research & Development , AbbVie , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Lake M; Research & Development , AbbVie , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Charych EI; AbbVie Neuroscience Research , 200 Sydney Street , Cambridge , Massachusetts 02139 , United States.
  • Stoll VS; Research & Development , AbbVie , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Sun C; Research & Development , AbbVie , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
  • Mohler EG; Research & Development , AbbVie , 1 North Waukegan Road , North Chicago , Illinois 60064 , United States.
J Med Chem ; 62(8): 4120-4130, 2019 04 25.
Article em En | MEDLINE | ID: mdl-30933499
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apolipoproteína E4 / Bibliotecas de Moléculas Pequenas Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apolipoproteína E4 / Bibliotecas de Moléculas Pequenas Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos