CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor.

Shoemaker, Christopher J; Huang, Tina Q; Weir, Nicholas R; Polyakov, Nicole J; Schultz, Sebastian W; Denic, Vladimir

Shoemaker, Christopher J; Huang, Tina Q; Weir, Nicholas R; Polyakov, Nicole J; Schultz, Sebastian W; Denic, Vladimir.

Afiliação

Shoemaker CJ; Department of Molecular and Cellular Biology, Harvard University, Northwest Labs, Cambridge, Massachusetts, United States of America.
Huang TQ; Department of Molecular and Cellular Biology, Harvard University, Northwest Labs, Cambridge, Massachusetts, United States of America.
Weir NR; Department of Molecular and Cellular Biology, Harvard University, Northwest Labs, Cambridge, Massachusetts, United States of America.
Polyakov NJ; Department of Molecular and Cellular Biology, Harvard University, Northwest Labs, Cambridge, Massachusetts, United States of America.
Schultz SW; Centre for Cancer Cell Reprogramming, Faculty of Medicine, University of Oslo, Oslo, Norway.
Denic V; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.

PLoS Biol ; 17(4): e2007044, 2019 04.

Article em En | MEDLINE | ID: mdl-30933966

Assuntos

Autofagia/genética; Autofagia/fisiologia; Proteínas de Membrana/genética; Sistemas CRISPR-Cas; Retículo Endoplasmático/metabolismo; Humanos; Células K562; Proteínas de Membrana/metabolismo; Proteínas de Membrana/fisiologia; Transporte Proteico

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Proteínas de Membrana Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Humans Idioma: En Revista: PLoS Biol Assunto da revista: BIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

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