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A cis-eQTL allele regulating reduced expression of CHI3L1 is associated with late-onset adult asthma in Japanese cohorts.
Kanazawa, Jun; Kitazawa, Haruna; Masuko, Hironori; Yatagai, Yohei; Sakamoto, Tohru; Kaneko, Yoshiko; Iijima, Hiroaki; Naito, Takashi; Saito, Takefumi; Noguchi, Emiko; Konno, Satoshi; Nishimura, Masaharu; Hirota, Tomomitsu; Tamari, Mayumi; Hizawa, Nobuyuki.
Afiliação
  • Kanazawa J; Department of Pulmonary Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, 305-8575, Japan.
  • Kitazawa H; Department of Pulmonary Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, 305-8575, Japan.
  • Masuko H; Department of Pulmonary Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, 305-8575, Japan. hmasuko@md.tsukuba.ac.jp.
  • Yatagai Y; Department of Pulmonary Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, 305-8575, Japan.
  • Sakamoto T; Department of Pulmonary Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, 305-8575, Japan.
  • Kaneko Y; Department of Pulmonary Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, 305-8575, Japan.
  • Iijima H; Tsukuba Medical Center, Amakubo 1-3-1, Tsukuba, Ibaraki, 305-8558, Japan.
  • Naito T; Tsukuba Medical Center, Amakubo 1-3-1, Tsukuba, Ibaraki, 305-8558, Japan.
  • Saito T; National Hospital Organization Ibaraki Higashi National Hospital, Terunuma 825, Tokai, Ibaraki, 319-1113, Japan.
  • Noguchi E; Department of Medical Genetics, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, 305-8575, Japan.
  • Konno S; Department of Respiratory Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita15, Nishi7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
  • Nishimura M; Department of Respiratory Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita15, Nishi7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
  • Hirota T; Research Center for Medical Science, The Jikei University School of Medicine, 3-25-8, Nishi-Shimbashi, Minato-ku, Tokyo, 105-8461, Japan.
  • Tamari M; Research Center for Medical Science, The Jikei University School of Medicine, 3-25-8, Nishi-Shimbashi, Minato-ku, Tokyo, 105-8461, Japan.
  • Hizawa N; Department of Pulmonary Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, 305-8575, Japan.
BMC Med Genet ; 20(1): 58, 2019 04 02.
Article em En | MEDLINE | ID: mdl-30940096
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Asma / Idade de Início / Locos de Características Quantitativas / Alelos / Proteína 1 Semelhante à Quitinase-3 Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Adult / Humans País/Região como assunto: Asia Idioma: En Revista: BMC Med Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Asma / Idade de Início / Locos de Características Quantitativas / Alelos / Proteína 1 Semelhante à Quitinase-3 Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Adult / Humans País/Região como assunto: Asia Idioma: En Revista: BMC Med Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão